JAMA: Can cardiovascular health improve metabolism in middle-aged people?

Recently, the Journal of the American Medical Association has now published an article on assessing the correlation between cardiovascular health (CVH) scores and hypertension, diabetes, chronic kidney disease, CVD and its subtypes (coronary heart disease, stroke, congestive heart failure, and peripheral artery disease), and advanced all-cause mortalityresearchers ask whether there is a correlation between the time of life in middle-aged people in the CHV state and the prognosis of cardiovascular metabolism and mortalityAnd carried out related research and data analysisthe prospective cohort study used data from 1,445 participants from 1991 to 2015 who participated in the community-based Framingham Heart Study in MassachusettsAssessed participants' CVH scores in the 5, 6 and 7 inspection cycles (1991-1995, 1995-1998 and 1998-2001, respectively)The median follow-up time is approximately 16 yearsCVH rating categories are: 0-7 poor, 8-11 points medium, 12-14 points betterThe overall score was based on smoking, diet, physical activity, resting blood pressure level, body mass index, fasting blood sugar levels and serum total cholesterol levelsThe main results after the seventh examination and the number of events and risks measured for each major result, including hypertension, diabetes, chronic kidney disease, cardiovascular disease and total cause mortalitystudy that included data from 1,445 middle-aged participants who had moderate or better CHV status every five years, were 33 percent less likely to have high blood pressure, 14 percent less likely to die from high blood pressure, and about 25 percent less likely to develop diabetes, chronic kidney disease or cardiovascular disease than people with poor CHV conditionsthe average age of 1,445 eligible participants was 60, of whom 751 (52%) were womenAfter the seventh examination, each major result (number of events/risk number of each major result) was: hypertension 348/795, diabetes 104/1304, chronic kidney disease 198/918, cardiovascular disease 210/1285 and total cause of death 300/1445In the seventh test, participants' CVH scores were mostly poor (568 (39%)) or moderate (782 (54%)For participants with a moderate or better CVH score, they were less likely to have adverse results (the risk ratio of hypertension was 0.67 (95% CI, 0.56-0.80), the risk ratio for diabetes was 0.73 ,95% CI, 0.57-0.93), and the risk ratio of chronic kidney disease was 0 75 .95% CI, 0.63-0.89, 0.73,95% CI, 0.63-0.85% for CVD, 0.86 for the whole cause mortality rate, and 0.86 for the total cause mortality rate, 95% of the confidence interval is 0.76-0.97No age or gender effects were observedresults suggest that improvements in cardiovascular health can extend life expectancy during the middle age And improving CHV in middle-aged people may be beneficial to heart metabolism and may reduce later mortality