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    Home > Medical News > Latest Medical News > JAK inhibitor Opzelura approved to treat atopic dermatitis

    JAK inhibitor Opzelura approved to treat atopic dermatitis

    • Last Update: 2021-09-29
    • Source: Internet
    • Author: User
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    CompilationFan Dongdong

    A few days ago, Incyte announced that the U.


    It is worth noting that Opzelura is the first and only topical JAK inhibitor approved by the US FDA


    However, a large number of studies have shown that dysregulation of the JAK-STAT pathway can cause the corresponding symptoms in patients with atopic dermatitis, including itching, inflammation and skin barrier dysfunction


    The test results showed that the most common (≥1%) adverse reactions in patients receiving Opzelura were nasopharyngitis, diarrhea, bronchitis, ear infections, increased eosinophil count, urticaria, folliculitis, tonsillitis, and rhinorrhea


    Todd Edwards, head of Incyte's inflammation and autoimmunity business unit, told investors in a conference call on Wednesday that, despite the black box warning, Incyte expects Opzelura's peak sales to reach at least $1.


    Wall Street also expects Opzelura cream to reach 1.


    Evercore ISI analysts recently pointed out that Opzelura is widely regarded as a key asset developed by Incyte to compensate for the loss of patent rights for its oral drug Jakafi in 2027


    In general, it is difficult for analysts to give clear answers on the future performance of Opzelura cream


    But on the other hand, given the power of Opzelura and the lack of topical options, doctors seem to show enthusiasm for the cream again


    In addition, the U.


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