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Depressive symptoms are associated with an increased risk of heart failure (HF), but their association with cardiac function and HF with preserved ejection fraction in later life (HFpEF) and decreased ejection fraction (HFrEF) is not yet clear
.
Recently, the heart blood vessels published a research article on the disease areas authoritative magazine JAHA, the researchers sought to determine the prevalence of depression in patients HFpEF and HFrEF, the association between depressive symptoms and cardiac function as well as events and HFpEF and HFrEF
.
The researchers analyzed 6,025 participants (age 75.
3±5.
1 years; 59% female; 20% black) in the ARIC (Community Atherosclerosis Risk) study, who received ultrasound at the fifth visit Cardiogram examination, and completed the Depression Scale Questionnaire of the Epidemiology Research Center
.
Among participants without HF (n=5086), the researchers used multivariate linear and Cox proportional hazards regression to assess the association between the epidemiological research center depression scale score and echocardiography and event determination HFpEF and HFrEF
Compared with participants without HF, HFpEF (but not HFrEF) was associated with a higher prevalence of depression (P<0.
001 and P=0.
59, respectively)
.
Among participants without HF, the scores of the Depression Scale of the Epidemiological Research Center were not related to the structure and function of the heart after adjusting for demographics and comorbidities (all P>0.
It can be seen that more severe depressive symptoms can predict the risk of HFpEF in later life, and have nothing to do with common comorbidities, cardiac structure and function, and prognostic biomarkers
.
Further research is needed to understand the mechanism of the association between depression and HFpEF risk
More severe depressive symptoms can predict the risk of HFpEF in later life, and have nothing to do with common comorbidities, cardiac structure and function, and prognostic biomarkers
Original source:
Katja Vu,et al.
Depressive Symptoms, Cardiac Structure and Function, and Risk of Incident Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction in Late Life in this message
