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JAHA: Platelet function linked to dementia risk

 Last Update: 2022-05-22
 Source: Internet
 Author: User

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The growing prevalence of Alzheimer's disease (AD), the most important form of dementia, requires biomarkers that can identify AD risk as early as middle age, when preventive interventions will be more effective

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The aim of this study was to investigate whether platelet function in middle-aged adults is independently associated with future AD risk

We assessed the association between baseline platelet function and dementia risk in the community-based FHS (Framingham Heart Study) longitudinal cohort

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The final study sample included 1847 FHS participants (mean age 53.

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CONCLUSIONS: At 20 years of follow-up, individuals with no antiplatelet therapy and higher platelet responses had a higher risk of dementia later in life, underscoring the role of platelet function in AD risk

Individuals not receiving antiplatelet therapy and with higher platelet responses have a higher risk of dementia later in life, underscoring the role of platelet function in AD risk

Original source:

Jaime Ramos‐Cejudo.

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