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JAHA: Dual antiplatelet therapy of cilostazol in patients with stroke and intracranial artery stenosis

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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In patients with intracranial arterial stenosis, the dual antiplatelet therapy (DAPT) in the prevention of recurrent stroke with a single antiplatelet therapy (SAPT) long-term benefits in the prevention of recurrent stroke has not been clear
.

Prevent stroke

Recently, the heart blood vessels published a research article on the disease areas authoritative magazine JAHA, the researchers aimed to compare the DAPT joint cilostazol and clopidogrel or aspirin efficacy in patients with intracranial arterial stenosis and SAPT clopidogrel or aspirin And safety
.

Heart blood vessels

These patients were recruited into the antiplatelet combined with cilostazol stroke prevention study, a randomized controlled trial conducted in Japanese patients at high risk of ischemic stroke
.

Researchers compared DAPT and SAPT in at least 50% of patients with ischemic stroke and symptomatic or asymptomatic intracranial arterial stenosis and bleeding events
.

The patients were divided into two groups: 275 were assigned to receive DAPT, and 272 patients were assigned to receive SAPT

Myocardial infarction

It can be seen that DAPT using cilostazol is superior to SAPT using clopidogrel or aspirin in preventing stroke recurrence and vascular events, and does not increase the risk of bleeding in patients with intracranial artery stenosis after stroke
.

DAPT using cilostazol is superior to SAPT using clopidogrel or aspirin in preventing stroke recurrence and vascular events, and does not increase the risk of bleeding in patients with intracranial artery stenosis after stroke
.

Original source:

Shinichiro Uchiyama.

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