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JAHA: Clinical value of chronic occult cerebral infarction and white matter hyperintensity in stroke, transient ischemic attack, and suspected stroke patients

 Last Update: 2022-02-19
 Source: Internet
 Author: User

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Recently , a research article was published in JAHA, an authoritative journal in the field of cardiovascular disease.
The study aimed to compare the frequency of chronic cerebral infarction (CBI) and white matter hyperintensity (WMH), and their association with transient ischemic attack (TIA).
) and the relationship between stroke-suspected patients and early recurrence risk score in ischemic stroke patients
.

Vascular stroke

This single-center cohort study included consecutive patients with TIA, suspected stroke, and acute ischemic stroke who underwent magnetic resonance imaging between January 2015 and December 2017
.

Blinded raters adjudicated subjects' WMH (age-related white matter change score) and CBI according to established definitions

The study included 2112 patients (median [Q1-Q3] age 71 [59-80] years, 43% female, NIH Stroke Scale score 2 [1-7], 80% ischemic stroke, 18% TIA, 2% suspected stroke patients) were included in the study
.

Although CBI was present in only 10% of patients with suspected stroke, CBI was detected in 28% of TIA and 38% of ischemic stroke patients (P<0.

CBI (adjusted odds ratio, 0.
3; 95% CI, 0.
1-0.
9) was associated with lower suspected stroke as a final diagnosis , whereas WMH was not (adjusted odds ratio, 1.
3; 95% CI, 0.
7-2.
2)
.

According to the ABCD3-I score, WMH (beta per score, 0.

diagnosis

CONCLUSIONS: CBI and WMH differed between patients with suspected stroke and those with TIA/ischemic stroke and were strongly associated with established recurrence risk scores
.

CBI and WMH differed between patients with suspected stroke and those with TIA/ischemic stroke and were strongly associated with established recurrence risk scores
.

Original source:

Alessandra Epstein.

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