JAHA: Association of diabetes with atrial fibrillation phenotype and cardiac and nervous system comorbidities

Diabetes is the main risk factor for atrial fibrillation (AF) .
The underlying mechanism linking diabetes to AF involves the electrical, structural and autonomic remodeling of the atrium
.
However, it is still unclear whether there are differences in the AF phenotype and related comorbidities of AF patients with and without diabetes

Recently, the heart blood vessels published a research article on the disease areas authoritative magazine JAHA, this study aimed to investigate the association between AF and AF phenotypes in patients with diabetes and heart and nervous system complications
.

The main outcome of the study is the parameters of the AF phenotype, including AF type, AF symptoms and quality of life (assessed by the European 5-Dimensional Quality of Life Questionnaire [EQ-5D]).
The secondary outcome of the study is the heart (ie, hypertension, Complications of myocardial infarction and heart failure) and nervous system (ie, history of stroke and cognitive impairment)
.
Researchers used logistic regression and linear regression to assess the cross-sectional association between diabetes and these outcomes, and adjusted for age, gender, and cardiovascular risk factors

The researchers included 2,411 AF patients (27.
4% were women; median age was 73.
6 years)
.
Diabetes is not associated with non-paroxysmal AF (odds ratio [OR] is 1.

It can be seen that compared with non-diabetic patients, AF patients with diabetes are less aware of AF symptoms, but have a poorer quality of life and more cardiac and nervous system complications
.

Original source:

Arjola Bano,et al.