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Mechanical take the first bolt on intravenous thrombolysis whether acute ischemic cerebrovascular stroke functional outcome has the added benefit of not yet clear
.
Recently, the heart blood vessels published on the prestigious journal JAHA the areas of disease research article, researchers conducted a meta-analysis, mechanical thrombectomy (dMT) with mechanical thrombectomy more direct intravenous thrombolysis joint bridging (bridging therapy [BT]) Efficacy in patients with acute ischemic stroke
.
Researchers searched the PubMed, Excerpta Medica database, and the Cochrane Central Registry of Randomized Controlled Trials.
The search time was from January 1, 2003 to April 26, 2021
.
The researchers included randomized clinical trials and observational studies that reported the 90-day functional outcome of patients with acute ischemic stroke who received dMT treatment compared to BT treatment
A total of 12 included studies (3 randomized controlled trials and 9 observational studies) were included in the analysis, with a total of 3924 subjects (mean age 68.
0 years [SD 13.
1 years]; 44.
2% females; 1887 participants Participants accepted dMT, 2037 participants accepted BT)
.
A meta-analysis of randomized controlled trials and observational data showed that subjects who received dMT and BT had 90-day functional independence (odds ratio [OR] 1.
Thus, in the meta-analysis of patients with acute ischemic stroke, researchers found that dMT and BT had no significant difference in 90-day functional outcome or mortality, but dMT had a lower rate of symptomatic intracranial hemorrhage
.
These results support the use of dMT instead of intravenous thrombolytic bypass therapy
In a meta-analysis of patients with acute ischemic stroke, the researchers found that dMT and BT had no significant difference in 90-day functional outcome or mortality, but dMT had a lower rate of symptomatic intracranial hemorrhage
Original source:
Houwei Du,et al.
Intravenous Thrombolysis Before Mechanical Thrombectomy for Acute Ischemic Stroke: A Meta-Analysis In this message
