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    Home > Active Ingredient News > Antitumor Therapy > J Urol: In patients undergoing robotic partial nephrectomy, what are the consequences of taking aspirin during the perioperative period?

    J Urol: In patients undergoing robotic partial nephrectomy, what are the consequences of taking aspirin during the perioperative period?

    • Last Update: 2021-10-20
    • Source: Internet
    • Author: User
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    Whether to stop aspirin or other antiplatelet therapies before major surgery needs to be weighed against the potential risk of bleeding and the possible increased risk of thrombotic events
    .


    A large randomized clinical trial (POISE2) on the use of aspirin in the perioperative period showed that the risk of major bleeding was increased, and the risk of death or non-fatal myocardial infarction was not significantly reduced


    Thrombosis Myocardial Infarction For urologists, the question of whether to stop taking aspirin before major surgery is still unresolved.


    Currently, patients in cardiac vascular intervention common aspirin treatment, but aspirin can cause bleeding risk, which also makes patients feel worried
    .


    Although aspirin protects the heart, it is usually stopped 5-7 days before surgery due to the risk of bleeding


    Heart blood vessels

    Recently, researchers from the United States published an article in the journal J Urol.
    They evaluated the results of perioperative use of aspirin (pASA) during RPN in a multi-center setting
    .

    They evaluated the results of perioperative aspirin (pASA) during RPN in a multicenter setting.
    They evaluated the results of perioperative aspirin (pASA) during RPN in a multicenter setting.

    Researchers evaluated patients receiving RPN in 5 high-volume RPN institutions
    .


    The perioperative results of patients taking pASA (81 mg) and not taking aspirin were compared


    Among the 1565 patients receiving RPN, 228 (14.
    5%) patients took pASA.
    They were older (62.
    8 years vs.
    56.
    8 years, p<0.
    001), and Charlson scores were higher (average 3 points vs.
    2 points, p <0.
    001)
    .


    pASA is associated with increased perioperative blood transfusion (11% vs.


    Postoperative results

    Postoperative results

    In summary, the perioperative use of aspirin during RPN is reasonable and safe, however, there is a higher risk of blood transfusion and major complications
    .


    In addition, in RPN patients who need pASA, future research needs to clarify the role of antiplatelet therapy to better achieve primary or secondary prevention of cardiovascular events .

    The use of aspirin during the perioperative period during RPN is reasonable and safe, however, there is a higher risk of blood transfusion and major complications


    Original source:

    Joan C Delto, Aaron Fleishman, Peter Chang et al.


    Perioperative Aspirin Use is Associated with Bleeding Complications During Robotic Partial Nephrectomy .


    Perioperative Aspirin Use is Associated with Bleeding Complications During Robotic Partial Nephrectomy

     

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