J Thromb Haemost: Prevalence of antiphospholipid antibody-positive in women at low risk of late pregnancy complications and chromosomal abnormalities.

Antiphospholipid antibodies (aPL) increase the risk of obstetric complications.
, however, the importance and prevalence of aPL in women with late pregnancy complications (LO-PC) needs to be further clarified.
Recently, a study published in Journal of Thrombosis and Haemostasis, the authoritative journal of thrombosis and clotting disease, looked at the prevalence of aPL among LO-PC women and compared it to normal pregnant women.
from August 2018 to August 2019, the study recruited 100 LO-PC women who had a low risk of chromosomal abnormalities and no risk of fetal abnormalities.
researchers used 100 women with good pregnancy conditions as a control group and conducted aPL tests on serum samples from prenatal screening, including standard and "super-standard" aPL.
the prevalence of aPL in LO-PC women was significantly higher than in the control group . . . 31/100 (31%) vs. 10/100 (10%) ;p .lt;0.001.
, as many as 26 per cent of LO-PC women had an aPL-positive, and the overall prevalence was significantly higher than in the control group (26 per cent vs. 9 per cent ;p-lt;0.05).
in individual aPL-positive women, their aCL IgG (10% vs. 2%; The positive and titration rates are higher at 4?9.6 CU;p?lt;0.05) and aPS/PT IgM (15% vs. 6%;
test aPS/PT (IgM/IgG) to identify 17 standard aPL-negative women.
risk of prenatal birth was significantly increased in women who were aPL-positive (34-36 plus 6w; 10% vs. 8% ;p.lt;0.012).
the study's queue reported a high prevalence of aPL.
standard and "extra standard" aPL testing of women with LO-PC in the past can improve diagnostic accuracy and thus help identify women at higher risk of recurrent pregnancy complications.
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