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People with hemophilia (PWH) are at risk of developing chronic hemophilic arthropathy (HA), a progressive disease caused by repeated intra-articular bleeding, followed by inflammation and damage to bone, cartilage, and other joint structures
Quality of Life
This multicenter , prospective, observational cohort study was designed to evaluate total hip (THA) or knee arthroplasty (TKA) Bleeding rate during the postoperative period
thrombus
We included patients with PWH of any severity ≥18 years of age who were receiving THA or TKA
Subjects underwent 131 procedures (98 TKA and 33 THA), of which 39 (29.
prevention
CONCLUSIONS: Despite coagulation factor supplementation, the risk of bleeding after THA and TKA in PWH patients remains high, and the use of antifibrinolytic drugs can reduce the risk
Despite coagulation factor supplementation, the risk of bleeding after THA and TKA in PWH patients remains high, and the use of antifibrinolytic drugs can reduce the risk
Original Source:
Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational
study