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    Home > Active Ingredient News > Blood System > J Thromb Haemost: Complications of postoperative bleeding in patients with hemophilia undergoing major orthopaedic surgery

    J Thromb Haemost: Complications of postoperative bleeding in patients with hemophilia undergoing major orthopaedic surgery

    • Last Update: 2022-03-02
    • Source: Internet
    • Author: User
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    People with hemophilia (PWH) are at risk of developing chronic hemophilic arthropathy (HA), a progressive disease caused by repeated intra-articular bleeding, followed by inflammation and damage to bone, cartilage, and other joint structures


    Quality of Life

    This multicenter , prospective, observational cohort study was designed to evaluate total hip (THA) or knee arthroplasty (TKA) Bleeding rate during the postoperative period


    thrombus

    We included patients with PWH of any severity ≥18 years of age who were receiving THA or TKA


    Subjects underwent 131 procedures (98 TKA and 33 THA), of which 39 (29.


    prevention

    CONCLUSIONS: Despite coagulation factor supplementation, the risk of bleeding after THA and TKA in PWH patients remains high, and the use of antifibrinolytic drugs can reduce the risk


    Despite coagulation factor supplementation, the risk of bleeding after THA and TKA in PWH patients remains high, and the use of antifibrinolytic drugs can reduce the risk


    Original Source:

    Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational

    study
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