J Rheumatol: Comparison of abdominal obesity with the risk of rheumatoid arthritis in ordinary obese women.

!---- Overweight or obesity increases the risk of rheumatoid arthritis (RA), especially among young women.abdominal obesity had a greater impact on systemic inflammation than normal obesity, the study looked at two prospective cohorts (NHS and NHS II) in which abdominal obesity predicted RA risk compared to common obesity.study followed 50,682 women in the NHS (1986-2014) and 47,597 women in NHS II (1993-2015), none of whom had RA at baseline.collected waist circumference (WC), body mass index (BMI), health outcomes, and covariate data through a biennial questionnaire.determine ra cases and serology through a medical record review. the-time-of-use denatured Cox scale risk model analyzed the correlation between WC and BMI and RA risk.repeated analysis of the population aged 55.identified 844 cases of RA patients (527 in the NHS, 317 in NHS II) over a 28-year follow-up period.women's waist circumference is 35 inches (88 cm) and the risk of RA is increased (HR 1.22, 95% CI 1.06-1.41).seropositive RA has observed similar associations, which are stronger in young and middle-aged women.adjusted the BMI further, the association is reduced to zero.by contrast, even after adjusting the WC, bmi was still associated with RA (HR BMI of 30 vs. .lt; 25 1.33, 95% CI 1.05-1.68) and seropositive RA, and, like THE WC analysis, the association was stronger in young and middle-aged women.abdominal obesity is associated with an increased RA risk in young and middle-aged women, especially serotonin-positive RA, but in addition to common obesity, abdominal obesity does not cause RA risk alone..