J Rheumatol: Airway and pulmonary substance lesions with primary dry syndrome
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Last Update: 2020-07-13
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Source: Internet
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Author: User
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The study was designed to assess the progression of lung function and chronic obstructive pulmonary disease (COPD) in patients with primary dry syndrome (pSS) over time, as well as the association between lung function, imaging, respiratory symptoms and pSS clinical characteristics, taking smoking into account40 pSS patients who participated in the pSS pulmonary cross-sectional study (average age 66 years, range 42-81 years, 39 females) who participated in the pSS pulmonary cross-sectional study, were re-evaluated for lung function after an average follow-up of 6 yearsAt the follow-up, chest high-resolution CT (HRCT) and pSS disease activity, respiratory symptoms, and smoking were also assessedpSS patients had a significant decrease in the percentage of lung (TLC), residual gas (RV), RV/TLC, and carbon monoxide dispersion (DLCO), while the baseline-followed 1 second rate (FEV1/VC) increased significantly as a percentage of the forecastThere was no significant change in the proportion of COPD from baseline to follow-up (38% vs.40%)Imaging signs of bronchial fatigue and interstitial pulmonary disease were found in 38% of patientsAirways and Pulmonary substance diseases are common in pSS patients, and obstructive and restrictive pulmonary dysfunction, which worsens over timeCOPD is still commonPSS airways and lungs may be affected by the possibility of missed diagnosis, so special attention must be paid to the clinical evaluation of lung conditions in pSS patients
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