J neurotrauma from tail to brain: intravenous treatment of brain injury

December 17, 2019 / biourn / -- researchers at the center for regenerative Biosciences at the University of Georgia found that neuroexosomes can be used as a means of intercellular communication and can minimize or even avoid traumatic brain injury The findings may help to develop regenerative therapy for TBI The research was published in Journal of neurotrauma recently, describing this new type of TBI regeneration treatment technology In particular, the new repair technology includes the biological manufacture of exosomes, which can be used as intravenous injection After entering the body, these exosomes become information carriers to reset, regenerate and coordinate communication with neighboring and distant cells The results showed that the new treatment significantly improved the functions of TBI rats "This technology takes full advantage of the ideal properties of neural stem cell therapy without introducing cells into patients," said Brooks, the author of the paper We are working to develop a multi-functional approach to repair brain damage and produce it in the form of cost-effective off the shelf drugs " (image source: www Pixabay Com) traumatic brain injury may be difficult to detect because each TBI patient presents a series of unique conditions, which depend on the time, severity, age, gender and occupation of the injury With this potential new technology, researchers hope to enhance the brain's natural recovery ability and provide doctors with immediate treatment for severe TBI cases For those patients affected by TBI, they can be treated when they are injured by intravenous infusion Using multiple small doses of intravenous injection, this new treatment aims to accelerate the regeneration of neurons and supporting cells after injury "Injecting exosomes into a patient's vein is more advantageous than invasive brain surgery," said Karen Baer, one of the authors Another application is the use of exosomes as a preventive management plan for TBI at all levels, including mild and moderate concussions, to minimize or prevent future damage To the brain, height from the vein: IV treatment for TBI original source: Min Kyong sun, Austin P passaro, Charles Francois latchoumane, Samantha E spelling, Michael bowler, Morgan goeden, William Jeffery Martin, Philip v Holmes, Steven L practice, Lohitash Karumbaiah Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury Journal of Neurotrauma , 2019; DOI: 10.1089/neu.2019.6443