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J Gastroenterology: Ursodeoxycholic acid may improve long-term prognosis in patients with primary sclerosing cholangitis

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease of unknown etiology characterized by progressive narrowing and destruction of the bile ducts due to diffuse inflammation and fibrosis, which eventually leads to cirrhosis and liver failure

The researchers retrospectively analyzed data from the Japanese PSC registry, which included 435 PSC patients

The results of the study showed that of the 435 patients with PSC, 110 were excluded due to insufficient or missing data, and the remaining 325 patients (male, 187 (58%); Mean age of diagnosis, 45.

This study confirmed that UDCA use was significantly associated with improved LT-free survival in patients with PSC, suggesting that UDCA improves long-term prognosis in patients with PSC

Original Source:

Toshihiko Arizumi.

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