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J Dermatolog Treat: Dupilumab can effectively improve the quality of life of patients with atopic dermatitis

 Last Update: 2021-05-20
 Source: Internet
 Author: User

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Atopic dermatitis (AD) severely affects the patient's quality of life (QoL).

The researchers analyzed the aggregated data of two phase 3 studies of the same design, LIBERTY AD SOLO 1 (NCT02277743) and SOLO 2 (NCT02277769), and assessed the following PROs: Numerical Rating Scale for Pruritus (NRS), Pruritus Classification Scale, SCORing AD (SCORAD), Dermatological Quality of Life Index (DLQI), Patient-Oriented Eczema Measurement (POEM), Hospital Anxiety and Depression Scale (HADS), Five-Dimension European Quality of Life Questionnaire (EQ-5D), and patient assessment Disease conditions and treatment effects.

The results showed that compared with placebo, dupilumab quickly improved the Peak Pruritus NRS score (p <.

In summary, the results of the study show that Dupilumab significantly improves AD symptoms, including itching, sleep, pain, anxiety and depression, and QoL in adults with moderate to severe AD.

Original source:

Michael J Cork, et al.

ncbi.
nlm.
nih.
gov/31179791/" target="_blank" rel="noopener">Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: analysis of pooled data from the randomized trials SOLO 1 and SOLO 2

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