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J Dermatolog Treat: Analysis of Disease Activity and Treatment Effects Using Patient-Level Psoriasis Area and Severity Index Scores in Phase 3 Clinical Trials

 Last Update: 2022-05-14
 Source: Internet
 Author: User

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Recently, several new drugs have been approved to treat moderate to severe plaque psoriasis

This post hoc analysis used tiralizumab 100 mg (N = 616) or placebo (N = 309) pooled patient-level data after treatment

RESULTS: The median baseline Psoriasis Area and Severity Index (PASI) was 17.

Taken together, the findings of this study suggest that the PASI score is more reliable for estimating disease activity than the percentage improvement in PASI; this may be partly responsible for the differences in efficacy between clinical trials and practice

Original source:

KB Gordon, et al.

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