J dental Res: Effects of oral microorganisms on physical health

February 9, 2021 /--- Healthy mouth includes not only clean teeth and hard gums, but also flora living in a blood vessel-rich environment that keeps organisms in constant contact with immune system cells and proteins.
Purnima Kumar, a professor of periodontal disease at Ohio State University, said in a report that there is growing evidence that the system, which appears to be so separate from the rest of our body, actually has a significant impact on and affects our overall health.
, for example, type 2 diabetes has long been known to increase the risk of gum disease.
recent studies have shown how diabetes affects bacteria in the mouth can help explain how periodontitis treatment, which alters oral bacteria, also reduces the severity of diabetes itself.
, the study also found a link between oral microbes and rheumatoid arthritis, cognitive abilities, pregnancy and heart disease, suggesting a link between oral bacteri groups and physical health.
(Photo: www.pixabay.com) The oral microbiome refers to a collection of bacteria that live in our mouths, some helpful to humans and some not to humans.
led and collaborated with Kumar on a recent study that further explains the link between oral health and type 2 diabetes.
the study compared the oral microbiome of people with and without type 2 diabetes and their response to non-surgical treatment for chronic periodontitis.
team found that periodontitis allows bacteria to control a mixture of microorganisms and inflammatory molecules in the mouth.
treatment of gum disease can eventually return to normal host-microbiome relations, but it occurs more slowly in diabetics.
s study concluded that people with diabetes have different microbiomes than non-diabetics," kumar said.
that changing the bacteria in your mouth and restoring them to healthy and friendly bacteria can actually improve your blood sugar control.
" although there is still much to learn, the basis for these relationships between the oral microbiome and systemic diseases is clear.
bacteria use oxygen to breathe and break down simple molecules of carbohydrates and proteins to sustain life.
simple thing as not brushing your teeth for a few days can trigger a series of changes that block the oxygen supply and cause microorganisms to turn into fermentation.
will create a fermentation environment that produces by-products and toxins that stimulate the immune system," Kumar said.
followed by an acute inflammatory reaction that produces a signal protein that bacteria think is food.
" and then the ecosystem changed.
that can break down proteins begin to grow more, and microbes that can breathe in oxygen-deprived environments begin to grow.
the characteristics of bacteria and, more importantly, the function of the immune system has changed."
opens pores between cells arranged between the mouths, and blood vessels leak, allowing unhealthy bacteria to enter the body's circulatory system.
"the body's response to these bacteria is producing inflammation, and these inflammatory products are moving into the bloodstream.
The exact mechanism by which the oral microbiome is linked to a particular disease is complex, but the secret to a healthy mouth is no secret: preventing oral diseases requires only oral hygiene, such as brushing your teeth and using cleaning tools such as flossing.
(Bioon.com) Source: Whats happens in the mouth ... doesn't stay in the mouth original source: P.S. Kumar et al. Subgingival Host-Microbial Interactions in Hyperglycemic Individuals, Journal of Dental Research (2020). DOI: 10.1177/0022034520906842