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J Clin Rheumatol: No significant difference in the risk of serious infections in rheumatoid arthritis with different JAK inhibitors

 Last Update: 2022-05-15
 Source: Internet
 Author: User

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JAKs kinases are cytoplasmic tyrosine kinases associated with membrane cytokine receptors, which mediate the signaling of various cytokines and growth factors, and are involved in the pathogenesis of various autoimmune diseases

Researchers searched PubMed, EMBASE, the Cochrane Library and clinicaltrials.

RESULTS: A total of 37 randomized controlled trials were included in the study

Taken together, the findings suggest that rheumatoid arthritis patients have a similar risk of developing serious infections among currently approved JAK inhibitor drugs

Original source:

Carlos Alves, et al.

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