 Home > Active Ingredient News > Antitumor Therapy > J Clin Oncol: The addition of carboplatin or bevacizumab to neoadjuvant chemotherapy for triple-negative breast cancer does not improve long-term outcomes (LTOs)

J Clin Oncol: The addition of carboplatin or bevacizumab to neoadjuvant chemotherapy for triple-negative breast cancer does not improve long-term outcomes (LTOs)

 Last Update: 2022-02-20
 Source: Internet
 Author: User

Tags

kill cancer

carboplatin code

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Recently, the Journal of Clinical Oncology published the long-term survival outcomes of the Phase II clinical study CALGB 40603 (NCT00861705)

Long-term outcomes (LTOs) of 443 treated patients were assessed using the Kaplan-Meier method

Of the 443 mITT population, 426 underwent surgery

In patients who achieved pCR (205/443, 46.

The addition of bevacizumab (HR, 0.

In conclusion, the CALGB 40603 study showed that the addition of carboplatin and bevacizumab did not improve LTOs in patients despite higher pCR rates

Original source:

Shepherd JH, Ballman K, Polley MC, Campbell JD, Fan C, Selitsky S, Fernandez-Martinez A, Parker JS, Hoadley KA, Hu Z, Li Y, Soloway MG, Spears PA, Singh B, Tolaney SM, Somlo G, Port ER, Ma C, Kuzma C, Mamounas E, Golshan M, Bellon JR, Collyar D, Hahn OM, Hudis CA, Winer EP, Partridge A, Hyslop T, Carey LA, Perou CM, Sikov WM.
CALGB 40603 (Alliance) : Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer.
J Clin Oncol.
2022 Jan 19:JCO2101506.
doi: 10.
1200/JCO.
21.
01506.
Epub ahead of print .
PMID: 35044810.

Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Crocetin27876-94-4

CAS No.: 27876-94-4

$1-1.1/G FOB

Betulinic acid472-15-1

CAS No.: 472-15-1

$1-1.1/G FOB

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 53-19-0

CAS No.: 53-19-0

Pharmacy Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.