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    Home > Active Ingredient News > Antitumor Therapy > J Clin Oncol: s18 F. fluorodeoxyglucose positron emission tomography scan/computer tomography on the stages of head and neck cancer and negative predictive value and surgical effects on the N0 neck

    J Clin Oncol: s18 F. fluorodeoxyglucose positron emission tomography scan/computer tomography on the stages of head and neck cancer and negative predictive value and surgical effects on the N0 neck

    • Last Update: 2020-07-13
    • Source: Internet
    • Author: User
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    The purpose of this study is to determine the negative prediction (NPV) of the clinical N0 neck based on the positive electron emission tomography (PET)/computertomic tomography (CT) on the basis of neck anatomyincluded participants in the newlydiagnosed, the first-time head and neck squamous cell carcinoma (HNSCC) and at least one clinical N0 neck side that planned an autopsyA total of 287 participants were forward-lookingly recruited from 23 American College of Radiological College imaging network qualification agenciesThe results of PET/CT were compared with those of neck anatomyresults, 212 participants had 270 Pet/CT scans and pathological results on the Neck Side of N0For visual evaluation, the NPV on the clinical-N0 side is 0.868 (95% CI, 0.803 to 0.925)For the maximum standardized intake values of the dicon method, the NPVs specificity of the nodule base is 0.940 (95% CI, 0.928 to 0.952) and 0.937 (95% CI, 0.925 to 0.949) at the pre-specified cutoff points of 2.5 and 3.5, respectivelyThe maximum standardized intake value for the best cutoff point was determined to be 1.8 and the NPV was 0.942 (95% CI, 0.930 to 0.953)Compared to PET/CT blind surgery, 51 (22%) of the 237 participants changed THE PET/CT informed surgical treatment regimenIn 34 participants (14%), this led to plans to dissect additional nodule levelsIn 12 participants (5%), this led to a decrease in the level of nodules planned for dissectionN0 neck PET/CT scan negative, 87% true negative, 13% false negativefluoro-deoxygenglucose-PET/CT has a higher NPV on the N0 neck of T2 to T4 HNSCCAbout 22% of patients in this group can change surgical treatment regimens based on PET/CT results These results show that the s/he-fluoro-oxycodone glucose-PET/CT can help clinicians determine the best treatment option for The N0 Neck of HNSCC clinically A well-designed clinical trial should be conducted to test the results of a neck anatomy that uses PET/CT to omit
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