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J Clin Oncol: Risk and associated risk factors for subsequent heart failure in childhood cancer survivors

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Heart failure (HF) is a potentially life-threatening complication of childhood cancer treatment, and the effects of low-dose drug therapy are currently poorly

The study included children diagnosed with cancer survivors aged 5 years and older between 1940 and 2009 in seven European countries (n=42361).

The results showed that by the age of 50, the cumulative incidence of heart failure was 2%.

As for the total cumulative dose of anthracyclines, the risk of heart failure was significantly increased in survivors receiving ≥ 100 mg/^m2, while the risk of heart failure was significantly increased

In summary, cancer survivors with an average cardiac radiation dose of ≥ 5 Gy have an increased

Original Source:

Esmée C.

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