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J Clin Oncol: Prognosis for patients with recurrent high-risk neuroblastoma with I/T/DIN/GM-CSF

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Although chemotherapy immunotherapy has been widely used in the treatment of high-risk neuroblastoma (HRNB) in children, the response time, duration, and progression after treatment with irinotecan/temozolomide/denutuximab/granulocyte-macrophage colony-stimulating factor (I/T/DIN/GM-CSF) are unknown

This retrospective study enrolled patients younger than 30 years of age who had previously received ≥ 1 course of I/T/DIN/GM-CB-CF for relapsed or refractory conditions

A total of 146 patients were included, and MYCN amplification

Patients were treated with a median course of 4.

Overall, approximately half of patients with recurrent high-risk neuroblastoma who received I/T/DIN/GM-CSF received objective remission

Original Source:

Benjamin J.

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