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    Home > Active Ingredient News > Immunology News > J Autoimmun : SB431542 relieves lupus nephritis by regulating B cells and inhibiting TLR9/TGFβ1/PDGFB signaling

    J Autoimmun : SB431542 relieves lupus nephritis by regulating B cells and inhibiting TLR9/TGFβ1/PDGFB signaling

    • Last Update: 2022-09-07
    • Source: Internet
    • Author: User
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    Lupus nephritis (LN) is the most common cause


    SB431542 protects renal function in NZB/W mice susceptible to lupus


    In summary, the study showed that SB431542 inhibited proteinuria and improved histological damage


     

    Source: Xia Y, Jiang C, Yang M, Liu T, Zou X, Li C, Wang X.


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