It specializes in "biting" human bones! People with low back pain should be careful of this blood tumor.

Back pain seems to have become the common disease of modern people regardless of men, women and children, young and middle-aged or old people are more or less present in these conditions some people may be purely not rest good some people may have waist disc protruding or people may be bone by tumor cells "bitten" this terrible The disease, called myeloma is a common blood system malignancies in Zhejiang University Medical College affiliated with the first hospital hematology 43-year-old Mr. Gong (analyte) how could not have imagined that he would suffer from multiple myeloma back pain butt pain, but the waist disc protruding? Lishui's Mr. Gong lay quietly in the first hospital bed by the door of the ward, which was closest to the bathroom, allowing him to walk a lot less, because for him, every move was torture.
first meeting Mr. Gong, he stared straight at the ceiling, and it was not until he spoke of his illness that he sat up and opened the box. Mr.
, who runs a design studio in his hometown and is both a "boss" and an "employee" and a local militiaman, was in good shape until the beginning of last year, when he insisted on donating blood every year and had no major problems with his body.
, he often felt pain in his buttocks.
"The first time it rained and slippery, I walked unsteady and cut a fork, and then I felt a little pain in my right ass."
, " Mr. Gong recalled, originally he thought it was a muscle pull, a few days later, the pain significantly eased, also did not take seriously.
later relatives asked me to help plug in, bent a day's waist, the next day on both sides of the thigh root pain can not.
"never inserted" Mr. Gong this time feel "tired" not light, lying for 2 days did not get out of bed before slowing down.
Although he was able to walk down, but the pain did not disappear, gradually, his buttocks and waist on both sides began to ache, and this pain is like running a marathon on the body running around, "feel the meat is hard."
" Mr. Gong pain is not good, to the local hospital, the doctor according to CT results diagnosed him for the waist disc protruding, compression nerves lead to pain, and gave him oral drugs, "I work every day in front of the computer to sit for 8 or 9 hours, when I said it is waist disc protruding, I want to see is not a big problem."
" but after taking more than a week of medicine, others are getting more and more uncomfortable, "sitting is not, standing is not, lying is not, is pain, often pain at night can not sleep."
" lingering pain, the culprit is that this blood malignant tumor pain really can not stand, Mr. Gong again to seek medical treatment for an MRI examination, the doctor told him that the result is highly suspected of the tumor and recommended to go to a major hospital.
's all unexpected! "It's over."
" in Mr. Gong's cognition, the tumor is equivalent to a terminal illness, he hid from the old mother at home, and his wife the next day went straight to Hangzhou, in a provincial hospital after a puncture examination was diagnosed with myeloma.
sure it's cancer, treat it well, " he said.
"already had psychological preparation, he was unusually calm, while relieving his wife, while looking for hope for himself.
when he learned that Zhejiang University Hospital Hematology is the year-on-year ranking of the country's top ten departments, immediately rushed to Zhejiang University Hospital, received the deputy director of hematology Yang Min physician.
" his puncture results showed that abnormal plasma cells accounted for more than 20% of bone marrow cells, in line with multiple myeloma myelin.
" Yang Min deputy director of the doctor introduced, Mr. Yan's diagnosis is more clear, at present, he has successfully received chemotherapy, good efficacy, pain significantly reduced, "patients like him because of his youth, the follow-up will be his own stem cell transplant."
" ranked second in the blood system malignant tumor multiple myeloma often disguised as these symptoms are not easy to distinguish, easy to misdiagnose, we must be alert to myeloma is a malignant tumor originating from bone marrow clone plasma cells, belongs to the blood system disease, good in the elderly, the average age of onset is about 65 years old.
" Dr. Yang Min introduced, may be many people have heard of leukemia, lymphoma, these blood diseases, myeloma is not very familiar with, but in fact, with people's attention to health, the emergence of an aging society, as well as the improvement of diagnostic technology, its incidence has an upward trend, in many countries ranked second in the blood system malignant tumors.
why is Mr. Gong only very common low back pain, bone pain, but was finally diagnosed with multiple myeloma? Dr. Yang Min deputy director of the introduction, multiple myeloma in the clinical performance of a variety of, it is easy to disguise as back pain, bone pain, anemia, urine foam and other manifestations, may be consulted in multiple departments, so often overlooked, it is easy to delay treatment or even misdiagnosis.
Bone pain is one of the most common manifestations of bone pain in all symptoms, which is related to myeloma cells secreting bone-breaking cell activity factors, which activate bone-breaking cells, destroy and dissolve bone, just like burying a "greedy worm" in the body, biting the bone out of a small round hole, causing bone pain in patients.
" is very similar to back pain caused by lumbar disc protrusion, osteoporosis, lumbar muscle strain, etc., so it is difficult for patients to distinguish.
" Dr. Yang Min said, like Mr. Yan in the first test did find the waist plate protruding and treatment, if not again to find the tumor, there is a good chance that the treatment will be delayed.
Anemia patients with multiple myeloma will also develop anemia, cancer cells inhibit the patient's hematosis function is one of the causes of anemia, and as the disease progresses may appear skin mucosa bleeding, bleeding gums and other different degrees of bleeding phenomenon.
and other important organs such as the kidneys and heart can also be affected by multiple myeloma, which is also a major organ.
Professor Jin Jie, director of the haematology department of Zhejiang University Hospital, reminds everyone that if there is unexplained bone pain, fractures, back pain, long-term anemia, abnormally elevated blood calcium, renal insanity and other symptoms, after ruling out all possible causes can not be diagnosed, we must promptly go to the blood disease specialist for examination.
treatment is diverse, the effect is ideal with the continuous progress of medicine, there are many ways to treat myeloma, but at present, the disease can not be completely cured.
" current treatment of multiple myeloma has moved from a traditional single chemotherapy model to a variety of treatment models.
" Professor Jin Jie introduced, chemotherapy, new targeted drug therapy, hematopoietic stem cell transplantation, CAR-T and other methods are used in the diagnosis and treatment of multiple myeloma.
hematopoietic stem cell transplant" a young patient like Mr. Gong, if evaluated to be eligible for transplantation, the self-hematopoietic stem cell transplant is very suitable for him.
" stem cells are a class of self-renewal ability of cells, autoimmune stem cell transplantation refers to the collection of a certain amount of stem cells, until chemotherapy drugs to remove myeloma cells in the body to the lowest point, and then back to the patient's stem cells to make blood, equivalent to a "self-help" method.
Despite the ongoing development of new drugs for myeloma, anthostoma transplantation is still the preferred treatment option for transplant patients in the Guidelines for the Diagnosis and Treatment of Multiple Myeloma in China (revised 2020).
addition to CAR-T therapy, CAR-T therapy has gradually become a new treatment, which is a way to use the patient's own T-cell decoration to fight tumor cells in the body.
hospital in Zhejiang Province, Zhejiang Province, has successfully completed clinical trials of CAR-T treatment of multiple myeloma since 2018, and has successfully completed the treatment of many patients.
with the development of science, the prognosis of treatment of patients with multiple myeloma has been getting better, and the patient's medium survival period has been generally extended, even for more than 10 years.
Lei Xiaomon Source: Zhejiang University Copyright Notice: All text, images and audio and video materials that indicate "Source: Mets Medicine" or "Source: MedSci Originals" are owned by Mets Medical and are not authorized, and may not be reproduced by any media, website or individual, and shall be reproduced with the authorization of "Source: Mets Medicine".
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