It is necessary to continue to study the evidence for expanding the scope of glioma excision

Ref: de Leeuw CN , et alNeuro Oncol2018 Oct 15doi: 10.1093/neuonc/noy166The results of the's recent results show that in glioma surgery, extended range removal of abnormal areas of MRI-T1 enhanced imaging and T2-FLAIR sequences can prolong patient survivalHowever, the quality of the evidence for these clinical trials is unclearCharles Nde Leew of Case Western Reserve University School of Medicine in Cleveland, Ohio, USA, and others conducted a systematic review of the literature on expanding the scope of glioma removal and published the results online in The Oncologe in October 2018the authors searched in the EMBASE, MEDLINE, Scopus, and Web of Science databases, except for case analysis, reviews or reviews, non-English-language articles, and literature containing only abstracts and brain metastasis, the authors included seven eligible research papers, including 492 glioma patients, including 214 cases of glioma in men and 278 women aged 18 to 82Of the 492 cases, 88 received an enlarged tumor excision, and tumor pathology was diagnosed with 51 cases of high-level glioma and 37 cases of low-level gliomaKarnofsky score, total survival, no progression survival, postoperative neurofunctional impairment and tumor-to-tumor degeneration conversion were used as the main prognosisauthors found through a comprehensive analysis that extended surgical removal, whether low-level or high-level gliomas, can prolong the overall survival and non-progressive survival of patients, but this is only preliminary low-level evidence; The authors suggest that prospective studies of larger sample sizes should be conducted to reduce potential bias and enhance the evidentiary effect.