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    Home > Biochemistry News > Plant Extracts News > It is found that rose fruit extract can treat triple negative breast cancer

    It is found that rose fruit extract can treat triple negative breast cancer

    • Last Update: 2015-04-09
    • Source: Internet
    • Author: User
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    Recently, a new study found that rose fruit, the extract of Rosaceae plant fruit, can significantly reduce the cell growth and migration of triple negative breast cancer Triple negative breast cancer is a particularly aggressive cancer that does not respond to the most effective treatment and tends to affect young women, as well as those of African or Hispanic origin Bioscience report: Recently, a new study found that rose fruit, the extract of Rosaceae plant fruit, can significantly reduce the cell growth and migration of triple negative breast cancer Triple negative breast cancer is a particularly aggressive cancer that does not respond to the most effective treatment and tends to affect young women, as well as those of African or Hispanic origin Extended reading: PNAs: three negative breast cancer "encounter the opponent" "Doctors, patients and researchers are looking for alternative therapies for triple negative breast cancer," said Patrick Martin, lead researcher and associate professor at North Carolina State University of agricultural technology People are always looking for ways to prevent cancer If you take vitamin tablets from rose plants every day, it may help to prevent or treat cancer, how wonderful you will think! We think it is an effective natural product without side effects " The name for triple negative breast cancer comes from the fact that cancer cells in these tumors lack the three growth factor receptors that are usually targeted during breast cancer treatment Therefore, at present, most of the treatments have no effect on it Compared with other types of breast cancer, three negative breast cancer patients in remission period have experienced higher recurrence rate and mortality in the first three years In this study, scientists used different concentrations of rose extract to treat three negative breast cancer cell culture Exposure to the highest concentration (1 mg / ml) reduced the proliferation of triple negative breast cancer cells by 50% With the decrease of concentration, the effect is weakened The highest concentration of rose fruit extract (0.025 to 1.0 mg / ml) reduced cell migration by 25% to 45% in triple negative breast cancer Additional experiments have shown that these extracts appear to work by reducing MAPK and Akt, two enzymes known to promote the growth of triple negative breast cancer cells The extract also improved the ability of adriamycin, a commonly used chemotherapy drug for breast cancer, to reduce cell proliferation and migration in tissue culture, indicating that rose fruit extract may be a beneficial supplement to the three negative breast cancer overall treatment program "I hope that we will use this study of tissue cultures, and future studies in animal models, to recommend Rosehip as a preventive measure for breast cancer, or as a supplement to current cancer treatments," Martin said Patrick Cagle, a doctoral student at Martin lab, said she felt a personal connection with the study: "I am a young African American woman, so I have a higher risk of triple negative breast cancer There are few studies on triple negative breast cancer and African American cancer, so we need to increase the visibility of this particular cancer in the scientific community and the public eye " Cagle will present the results of this study at the society for pharmacology and experimental therapeutics (aspet) of the 2015 American annual conference on experimental biology African American women with triple negative breast cancer have a particularly poor outlook, which Cagle says is one area that needs further study Scientists speculate that this difference may be related to biological and genetic differences, including the prevalence of risk factors, barriers to access to health care, healthy behavior or the fact that African American patients are often diagnosed with breast cancer in the late stage Rose fruit, the round part of a rose, directly below the petals, is used as a natural source of vitamin C in tea and other foods In the experiment, researchers used pure rose fruit, which can be sold as a pill supplement or liquid form The breast cancer study came out of a previous study in which researchers used rose fruit extract to successfully block the growth of brain tumor cells, one of which is where triple negative breast cancer spreads They also want to test the effect of the extract on prostate cancer cells.
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