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▎The editing eyes of WuXi AppTec's content team are the windows of the human soul, through which not only can observe the world, but also express rich emotions
.
However, with age, the eyes, the window of the soul, are susceptible to many diseases, such as age-related macular degeneration (AMD), cataracts, and diabetes-related eye disease (DRED), which cause the eyes to lose their color
.
In fact, these eye diseases not only affect vision, but also cause more harm
.
According to a study published by researchers from the Guangdong Academy of Medical Sciences and other institutions, eye diseases related to age-related macular degeneration, cataracts and diabetes are associated with an increased risk of dementia
.
Moreover, these eye diseases can interact with diabetes, hypertension, stroke, etc.
, further increasing the risk of dementia
.
The study was published in the British Journal of Ophthalmology, and the corresponding authors are Dr.
He Mingguang and Dr.
Yang Xiaohong from the Department of Ophthalmology, Guangdong Academy of Medical Sciences
.
Image source: 123RF The data for this study comes from the UK biobank.
A total of 12364 subjects aged 55-73 were included.
Their average age was 62.
4 years old and 54.
0% were women
.
The researchers collected the subjects’ basic health information (age, gender, etc.
); life>
.
During the average follow-up period of 11 years, there were 2304 new cases of dementia, including 945 cases of Alzheimer's disease and 513 cases of vascular dementia
.
Image source: After 123RF adjusted for other factors, researchers found that eye diseases are associated with an increased risk of dementia: Compared with subjects who did not suffer from age-related macular degeneration, subjects with age-related macular degeneration were associated with dementia A 26% increase in risk is associated; compared with subjects without cataracts, cataracts are associated with an 11% increase in risk of dementia; compared with subjects who do not have diabetes-related eye diseases, they have diabetes-related eye diseases, It is associated with a 61% increase in the risk of dementia; compared with subjects without glaucoma, having glaucoma is associated with a 7% increase in the risk of dementia
.
However, there is no statistically significant difference between glaucoma and increased risk of dementia
.
At the same time, the study also found that compared with subjects who did not have eye diseases and systemic diseases, subjects who had both eye diseases and systemic diseases had a higher risk of developing dementia
.
For example, compared to subjects without age-related macular degeneration and diabetes: only age-related macular degeneration is associated with a 22% higher risk of dementia; only diabetes is associated with an increased risk of dementia 99 % Related; having age-related macular degeneration and diabetes at the same time is related to a 173% increase in the risk of dementia
.
Compared with subjects without age-related macular degeneration and any systemic disease: only age-related macular degeneration is associated with a 20% higher risk of dementia; only one systemic disease, It is associated with a 43% increase in the risk of dementia; both age-related macular degeneration and at least one systemic disease are associated with an 83% increase in the risk of dementia
.
Image source: 123RF researchers analyzed that age-related macular degeneration and other ophthalmic diseases may have an impact on the risk of dementia through a variety of biological mechanisms
.
For example, eye diseases are related to the risk factors of dementia, including diabetes, stroke, etc.
, which may affect the risk of dementia through these risk factors; visual disturbances caused by eye diseases may cause the central nervous system to decrease and increase the sensory pathway stimulation.
Cognitive load and the risk of brain damage, which in turn affect the risk of dementia
.
However, the relevant biological mechanisms have not yet been clarified, and further research and exploration are needed
.
Since the study is an observational study, it only shows the association between eye diseases and the risk of dementia, and does not indicate a causal relationship.
Moreover, the study has limitations.
Researchers have confirmed that some patients may have eye diseases but are not aware of them, which may also have an impact on the results of the study
.
However, the researchers pointed out, "The results of this study show that eye diseases are associated with an increased risk of dementia; people who suffer from both eye diseases and systemic diseases are at a higher risk of dementia
.
"
This means that "people who suffer from both eye diseases and systemic diseases should be the target of prevention and screening for dementia in the elderly
.
"
It is recommended to read the three major misunderstandings of body fat and blood fat.
Everyone should know how to prevent stroke and eat peanuts? With 4-5 tablets per day, the risk of stroke may be reduced by 16%.
Shanghai Ruijin Hospital Research: These 12 risk factors increase the risk of diabetes! How many kinds do you have? Data of 2 million people, dementia is related to noise! Protecting hearing helps prevent dementia? Longer and longer life! New research adds evidence: 7000 steps per day may reduce the risk of death by more than half.
References[1] Xianwen Shang, et al.
,(2021).
Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank.
British Journal of Ophthalmology , DOI: http://dx.
doi.
org/10.
1136/bjophthalmol-2021-319508.
[2] Eye conditions linked to heightened risk of dementia.
Retrieved Sep 15 ,2021,from https://medicalxpress.
com/news/ 2021-09-eye-conditions-linked-heightened-dementia.
htmlDisclaimer: WuXi AppTec's content team focuses on introducing global biomedical health research progress
.
This article is for the purpose of information exchange only.
The opinions expressed in the article do not represent the position of WuXi AppTec, nor does it mean that WuXi AppTec supports or opposes the views in the article
.
This article is not a treatment recommendation either
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
.
However, with age, the eyes, the window of the soul, are susceptible to many diseases, such as age-related macular degeneration (AMD), cataracts, and diabetes-related eye disease (DRED), which cause the eyes to lose their color
.
In fact, these eye diseases not only affect vision, but also cause more harm
.
According to a study published by researchers from the Guangdong Academy of Medical Sciences and other institutions, eye diseases related to age-related macular degeneration, cataracts and diabetes are associated with an increased risk of dementia
.
Moreover, these eye diseases can interact with diabetes, hypertension, stroke, etc.
, further increasing the risk of dementia
.
The study was published in the British Journal of Ophthalmology, and the corresponding authors are Dr.
He Mingguang and Dr.
Yang Xiaohong from the Department of Ophthalmology, Guangdong Academy of Medical Sciences
.
Image source: 123RF The data for this study comes from the UK biobank.
A total of 12364 subjects aged 55-73 were included.
Their average age was 62.
4 years old and 54.
0% were women
.
The researchers collected the subjects’ basic health information (age, gender, etc.
); life>
.
During the average follow-up period of 11 years, there were 2304 new cases of dementia, including 945 cases of Alzheimer's disease and 513 cases of vascular dementia
.
Image source: After 123RF adjusted for other factors, researchers found that eye diseases are associated with an increased risk of dementia: Compared with subjects who did not suffer from age-related macular degeneration, subjects with age-related macular degeneration were associated with dementia A 26% increase in risk is associated; compared with subjects without cataracts, cataracts are associated with an 11% increase in risk of dementia; compared with subjects who do not have diabetes-related eye diseases, they have diabetes-related eye diseases, It is associated with a 61% increase in the risk of dementia; compared with subjects without glaucoma, having glaucoma is associated with a 7% increase in the risk of dementia
.
However, there is no statistically significant difference between glaucoma and increased risk of dementia
.
At the same time, the study also found that compared with subjects who did not have eye diseases and systemic diseases, subjects who had both eye diseases and systemic diseases had a higher risk of developing dementia
.
For example, compared to subjects without age-related macular degeneration and diabetes: only age-related macular degeneration is associated with a 22% higher risk of dementia; only diabetes is associated with an increased risk of dementia 99 % Related; having age-related macular degeneration and diabetes at the same time is related to a 173% increase in the risk of dementia
.
Compared with subjects without age-related macular degeneration and any systemic disease: only age-related macular degeneration is associated with a 20% higher risk of dementia; only one systemic disease, It is associated with a 43% increase in the risk of dementia; both age-related macular degeneration and at least one systemic disease are associated with an 83% increase in the risk of dementia
.
Image source: 123RF researchers analyzed that age-related macular degeneration and other ophthalmic diseases may have an impact on the risk of dementia through a variety of biological mechanisms
.
For example, eye diseases are related to the risk factors of dementia, including diabetes, stroke, etc.
, which may affect the risk of dementia through these risk factors; visual disturbances caused by eye diseases may cause the central nervous system to decrease and increase the sensory pathway stimulation.
Cognitive load and the risk of brain damage, which in turn affect the risk of dementia
.
However, the relevant biological mechanisms have not yet been clarified, and further research and exploration are needed
.
Since the study is an observational study, it only shows the association between eye diseases and the risk of dementia, and does not indicate a causal relationship.
Moreover, the study has limitations.
Researchers have confirmed that some patients may have eye diseases but are not aware of them, which may also have an impact on the results of the study
.
However, the researchers pointed out, "The results of this study show that eye diseases are associated with an increased risk of dementia; people who suffer from both eye diseases and systemic diseases are at a higher risk of dementia
.
"
This means that "people who suffer from both eye diseases and systemic diseases should be the target of prevention and screening for dementia in the elderly
.
"
It is recommended to read the three major misunderstandings of body fat and blood fat.
Everyone should know how to prevent stroke and eat peanuts? With 4-5 tablets per day, the risk of stroke may be reduced by 16%.
Shanghai Ruijin Hospital Research: These 12 risk factors increase the risk of diabetes! How many kinds do you have? Data of 2 million people, dementia is related to noise! Protecting hearing helps prevent dementia? Longer and longer life! New research adds evidence: 7000 steps per day may reduce the risk of death by more than half.
References[1] Xianwen Shang, et al.
,(2021).
Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank.
British Journal of Ophthalmology , DOI: http://dx.
doi.
org/10.
1136/bjophthalmol-2021-319508.
[2] Eye conditions linked to heightened risk of dementia.
Retrieved Sep 15 ,2021,from https://medicalxpress.
com/news/ 2021-09-eye-conditions-linked-heightened-dementia.
htmlDisclaimer: WuXi AppTec's content team focuses on introducing global biomedical health research progress
.
This article is for the purpose of information exchange only.
The opinions expressed in the article do not represent the position of WuXi AppTec, nor does it mean that WuXi AppTec supports or opposes the views in the article
.
This article is not a treatment recommendation either
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
