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Multiple sclerosis (MS) is the most common inflammatory demyelinating disease of the central nervous system
In the new technology library, two three-dimensional T1-weighted magnetic resonance (MR) brain sequences MP2RAGE (Magnetization Preconditioning 2 Fast Acquisition Gradient Echo) and its derived FLAWS (fluid and white matter suppression) technology have shown significant effects on cortical or white matter (WM) Significantly high sensitivity for lesion detection
FLAWS is an MP2RAGE-derived sequence whose modified TI achieves first-contrast WM signal suppression, resulting in a composite 2-image combination with enhanced contrast
A study published in the journal Investigative Radiology evaluated cervical MS lesions on a CS-accelerated FLAWS sequence of 1 mm isotropic resolution obtained in 5 minutes and 40 seconds compared to reference sagittal and axial T2-weighted TSE scans.
The results of this study demonstrate that CS-FLAWS imaging can significantly improve the detection of cervical cord lesions in MS with high confidence in clinically acceptable scan times, leading to a faster, more comprehensive, and more reliable MR workflow in MS imaging paved the way
Original source:
Thibaut Emorine, Imen Megdiche, Pierre Brugières, et al.