[inventory] in recent years, "Chinese Academy of Sciences system" ~ drug registration

The Chinese Academy of Sciences, with the birth of new China, has made irreplaceable and important contributions to China's scientific and technological progress, economic development and national security As the highest academic institution of Chinese natural science, the highest consulting institution of science and technology, and the comprehensive research and development center of natural science and high technology, the research and development direction of Chinese Academy of Sciences covers almost all fields The research and development of medicine related to human life science is naturally one of its important directions Through the inquiry, it is found that some departments in the whole system of CAS are involved in drug research and development, and many varieties have become the benchmark in the industry Therefore, whether it is research strength or development ability, it can be said that the Chinese Academy of Sciences is leading the development of national pharmaceutical industry to a certain extent 1 The overall distribution of system drug registration of Chinese Academy of Sciences is inquired by the drug intelligence data Since 2001, there have been 12 institutes related to system and drug registration of Chinese Academy of Sciences, with 142 pieces of total registration information The annual drug application approval situation is shown in the figure below: Figure 1: in recent years, the application approval situation of system drug of Chinese Academy of Sciences The 12 research institutes and their corresponding registered information are respectively Shanghai Institute of Medicine (98), Shanghai Institute of Organic Chemistry (13), Kunming Institute of Botany (9), Shanghai Institute of Biochemistry (4), Institute of Botany, Jiangsu Academy of Sciences (4), Shenyang Institute of Applied Biology (3), Changchun Institute of Applied Chemistry (3), Lanzhou Institute of Chemical Physics (3) (2 articles), Shanghai Institute of Life Sciences (2 articles), Xinjiang Institute of physical and Chemical Technology (2 articles), Shanghai Institute of Plant Physiology (1 article), Institute of Biochemistry and cell biology (1 article) See the following figure for details: Figure 2: drug registration of each Research Institute in the system since 2001 In terms of the distribution of treatment fields, the whole CAS system covers a wide range Relatively speaking, there are a large number of anti-tumor drugs, immunomodulators and nervous system drugs See the following figure for details: Figure 3: the distribution of CAS system drug R & D and treatment fields 2 CAS system ~ chemical drug registration [chemical drug registration category 1] Through drug intelligence data query, there are 44 registration information of class 1 drugs, including Shanghai Institute of medicine and Kunming Institute of Botany, Chinese Academy of Sciences; there are 19 varieties involved, most of which have been approved for clinical use; among them, 11 are special approved varieties, and 3 are major special varieties See the following table for details: Table 1: acceptance of class 1 registration of chemical drugs (select one representative acceptance information for each variety, the same below) ☆ chemical registration category 2 Through drug intelligence data query, there are 11 registration information of class 2 drugs, including Institute of chemistry, Shanghai Institute of organic chemistry and Shanghai Institute of drugs of Chinese Academy of Sciences; there are 8 varieties involved, all of which have been approved for clinical application; the application time is concentrated between 2000 and 2005, and the details are shown in the following table: Table 2: acceptance of class 2 registration of chemical drugs ☆ class 3 registration of chemical drugs Through drug intelligence data query, there are 10 types of drug registration information, including Shanghai Institute of medicine and Shenyang Institute of Applied Ecology; there are 6 types involved, all of which have been approved for clinical application; the application time is concentrated between 2004 and 2006, and the details are shown in the following table: table 3: acceptance of type 3 chemical registration 3 Registration of biological medicine traditional Chinese medicine natural medicine system of Chinese Academy of Sciences The Chinese Academy of Sciences also has extensive involvement in biological medicine, traditional Chinese medicine and natural medicine, but the overall state is far less than the input and output of chemical medicine In terms of crude drugs, the main research and development units are Shanghai Institute of life sciences, Shanghai Institute of Biochemistry and Shanghai Institute of plant physiology; in terms of traditional Chinese medicine, the main research and development units are Shanghai Institute of Biochemistry, Jiangsu Academy of Chinese Sciences Institute of Botany, Kunming Institute of Botany, Shanghai Institute of medicine, Xinjiang Institute of physical and chemical technology, Changchun Institute of chemistry and physics, Lanzhou Institute of chemistry and physics, and Biology Institute of chemistry and cell biology, see the following table for details: Table 4: acceptance of registration of biological medicine - traditional Chinese Medicine - Natural Medicine 4 Summary + exclamation: from the perspective of drug registration, the development of the Chinese Academy of Sciences system for drugs has been widely involved in the early years and concentrated on the road of class 1 new drug creation, which to a certain extent greatly responds to the national policy In terms of new drug development, it is almost fully covered by Shanghai drugs, which is also in line with its influence in the industry for many years Seeing the contribution of CAS system to drug research and development over the years, I have a lot of imagination... I remember how I wanted to be a member of CAS as early as I was a undergraduate, and I hope to devote my youth and life to it I feel that it will be a very meaningful thing.. Although my dream has not been realized, today's work can really touch the new drug creation , we can get closer to science through our own efforts.. Ha ha! Suddenly found ~ youth? Life? How can there be so many perfections? How similar it is to the creation of new drugs! Full of challenges! Pain and happiness exist! Note: the data in this paper are all from the data of pharmaceutical intelligence!