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For more gastroenterology drugs, go to the "Clinical Decision Assistant App"!
Following montmorillonite, norfloxacin has also appeared on the "hot search", norfloxacin, as an antibacterial agent of quinolones, suitable for urinary tract infections, gonorrhea, prostatitis, intestinal infections, typhoid and other salmonella infections caused by sensitive bacteria [1-3].
Gastroenterology with norfloxacin, clinical decision-making assistant - evidence-based medication points out these 5 safe medication precautions!
(1) Since Escherichia coli is currently more common in norfloxacin resistance, urine samples should be taken for culture before administration, and medication should be adjusted with reference to bacterial susceptibility results [1][3].
(2) When this product is applied in large doses or when the urine pH value is above 7, crystalline urine
can occur.
In order to avoid the occurrence of crystalline urine, it is advisable to drink more water and maintain a 24-hour urine output of more than 1200ml [1-3].
(3) Patients with glucose-6-phosphate dehydrogenase deficiency take this product, and hemolytic reactions may occur in rare cases [1-3].
(4) Disabling and potentially irreversible serious adverse reactions, including tendonitis and tendon rupture, peripheral neuropathy, central nervous system effects: With fluoroquinolones, simultaneous disabling and potentially irreversible serious adverse reactions have been reported in different organ systems of the same patient's body, usually including: tendonitis, tendon rupture, arthralgia, myalgia, Peripheral neuropathy and central nervous system reactions (hallucinations, anxiety, depression, insomnia, severe headache and confusion).
These adverse effects can occur hours to weeks
after norfloxacin capsules.
These adverse effects have been reported in patients of any age with no prior associated risk factors [1-3].
(5) In the course of long-term treatment, organ system function, including kidney, liver and hematopoietic function should be regularly evaluated [2].
How to adjust the dose of norfloxacin for special groups such as liver and kidney injury, the elderly, and children?
What are the symptoms of an allergic reaction to norfloxacin? How to deal with it?
Open "Clinical Decision Assistant - Evidence-based Medicine" to search for related disease names/drug names, one click directly! 👇
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References: [1] Drug information: norfloxacin capsules, Harbin Zhenbao Pharmaceutical Co., Ltd.
, Sinopharm H23020506; 2020/12/30.
[2] Drug information: norfloxacin tablets, CSPC Ouyi Pharmaceutical Co.
, Ltd.
, Sinopharm H13022722; 2020/12/30.
[3] Drug information: norfloxacin glucose injection, Zhejiang Jimin Pharmaceutical Co.
, Ltd.
, Sinopharm H20013172; 2015/09/14.
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