International market expansion of medicinal plant extracts

Plant extracts are the key category of API exhibition As a product of "natural medicine" and "homeopathy", plant extracts have a very stable market in western countries and developing countries In 2009, the most remarkable export growth was the sweetener plant extracts led by stevioside, compared with the export of most of the medicinal plant extracts Statistics show that Zhejiang, Beijing and other provinces, which mainly produce medicinal plant extracts, have seen a small decline in the amount of exports However, after many years of observation, the export of medicinal plant extracts is still stable and has been recognized by the international market in recent years Ephedrine: strong demand for natural products due to the development of low-cost synthetic ephedrine products in Germany and other developed countries Now many pharmaceutical manufacturers in western countries are using synthetic ephedrine to replace natural ephedrine, which makes the export of ephedrine in China face a new impact However, because natural ephedrine is better than synthetic ephedrine in weight loss, a large amount of natural ephedrine still needs to be imported from European and American countries, so there is still a huge development space in the international market for natural ephedrine in China According to statistics, the total demand for natural ephedrine (extract powder) in the international market in recent years is about 2500 tons, with a large market gap In 2009, the United States imported 800 tons of ephedrine from China and Europe imported 500 tons of ephedrine from China Due to the promising international market, some manufacturers have invested heavily in the establishment of Ephedra planting and extraction bases in Inner Mongolia and other places At the same time, domestic manufacturers have also made great efforts in the field of synthetic ephedrine Last year, Zhejiang PLO Kangyu Pharmaceutical Co., Ltd cooperated with Shanghai Pharmaceutical Industry Research Institute to build a new production line with an annual output of 500 tons of synthetic ephedrine in Zhejiang, which makes China rank in the forefront of the world's major synthetic ephedrine countries Paclitaxel: Paclitaxel is the best-selling raw material product of natural anticancer drugs in the international market in the past 20 years In 2007, the turnover of paclitaxel in the international pharmaceutical market was US $195 million Due to the production of semi synthetic taxol in Western European countries such as France and Italy, the total output of taxol APIs in the world is estimated to be 700-800 kg, of which natural taxol accounts for less than 15% According to the prediction of foreign pharmaceutical industry, by 2012, the total output of paclitaxel in the world will reach 1040 kg, with an annual demand growth rate of 10% As Paclitaxel injection combined with cancer drug Herceptin can significantly prolong the survival time of patients with advanced breast cancer and ovarian cancer, it is expected that the international market for half synthetic paclitaxel APIs will continue to maintain a rapid growth momentum In the south of China, there has been a cultivation base of more than 100000 mu of fast-growing Taxus plantation Theoretically, the annual production of semi synthetic taxol from the whole plant of fast-growing Taxus in China is at least 500 kg, but only one Jiangsu Hongdou pharmaceutical company has completed the industrialization of semi synthetic taxol It is estimated that the annual production capacity of semi synthetic taxol is about 150 kg at present Because of the huge demand for paclitaxel API in China, the domestic paclitaxel API manufacturers mostly produce and sell their own products, and the number of export paclitaxel APIs is small This situation is in sharp contrast with the large export of ephedrine extract powder in China At present, the fast-growing Taxus forest in Hunan, Hubei and Guizhou has entered the cutting period It is estimated that in the next few years, the production of taxol API in China will increase significantly, and become an important exporter of taxol API in the international market Angelica extract: Chinese medicine believes that Angelica has a strong effect of promoting blood circulation and removing blood stasis, but what foreign scholars really pay attention to is its excellent effect of reducing blood viscosity Angelica extract has always been one of the most popular natural plant extracts in the market of the United States and other developed countries It is estimated that the total export volume of angelica extract in China is about 2000 kg per year, and the export volume is very stable It is worth noting that the research team led by Professor Lv Guiyuan of Zhejiang University of traditional Chinese medicine has found that angelica extract has obvious antihypertensive effect Professor Lu's research achievements have won the second prize of national science and technology invention and attracted great attention of the pharmaceutical industry abroad If it is used for antihypertensive purposes, it is believed that angelica extract will usher in greater growth space in the future, thus greatly promoting the new upsurge of Angelica cultivation in China In addition to the above varieties, in the past two years, some of the smaller Chinese herbal extracts in China are also very popular in foreign countries These small varieties of products mainly include: Scutellaria (baicalin), Schisandra chinensis (schisandrin), Polygonum cuspidatum (resveratrol), Centella asiatica (asiaticoside), acanthopanax senticosus (Acanthopanax senticosus), Epimedium (icariin), Hypericum perforatum (hypericin), fairy extract, Pueraria (puerarin flavonoids), white ginseng, Cordyceps, pilose antler, tea polyphenols, etc According to the statistics of the U.S Customs, in recent years, the amount of plant extracts from Chinese herbal medicines imported by the United States from China has been kept at 120 million to 150 million US dollars; as many as 60 varieties of extracts from Chinese herbal medicines have been imported, which shows that Chinese herbal extracts have been generally recognized by American manufacturers Link > > > the three natural sweeteners led the export matrix in 2009, in the export of plant extracts in China, stevioside, glycyrrhizin and siraitin three natural sweetener plant extracts stand out from many varieties Stevioside has long been suppressed by sweetener manufacturers such as aspartame in the United States Until the experts of the American Medical Association published a paper in recent years, it was pointed out that regular consumption of foods containing aspartame can induce Alzheimer's disease, Parkinson's disease and other brain neuropathy symptoms Stevioside as a natural harmless sweetener has really attracted attention In recent years, stevioside in China has become more and more popular in American market According to customs statistics, in 2006, China exported more than 20 million US dollars of stevioside; in 2009, China exported as much as 84.3 million US dollars of stevioside, 1754 tons, 84 times more than in 2000 Both the amount and the quantity are the best in history As many provinces and regions in China have established large-scale Stevia planting bases, it is expected that the export of stevioside in China will continue to be optimistic in the next few years, and the export amount is expected to exceed US $100 million, becoming the leading product in the export of plant extracts The sweetness of rhG is about 300 times of that of white sugar, and the sweetness is pure Japanese scholars recognized the potential value of Siraitia grosvenorii as a new natural sweetener as early as 1980s, and since then, they have been importing Siraitia grosvenorii from China Since Guilin No.1 company first developed high-purity Luohanguo glucoside as a natural food sweetener, its brand of Luohanguo glucoside quickly opened up the European and American markets, and led to a boom in Luohanguo planting in Guangxi and other provinces According to statistics, in 2009, the annual output of Siraitia grosvenorii in China has reached 160 million pieces, the total output of Siraitia grosvenoride is about 400 tons, and the export volume is about 350 tons American and European Union manufacturers imported rohangoside from China, which is mainly used in food and beverage, to replace aspartame, saccharin and other chemical synthetic sweeteners In addition, Japanese manufacturers also use imported Chinese Luohanguo glucoside and Guangxi sweet tea and other plant extracts to process new health care products such as anti allergy drinks with excellent market Glycyrrhizin glycyrrhizin is the first major sweetener plant extract product exported in China However, due to the long-term indiscriminate mining in the licorice producing areas, the wild licorice resources in China have been on the verge of exhaustion, and now the licorice in the market is mostly planted artificially The United States is the world's largest licorice market, importing about 12000 tons of fresh licorice and 4500 tons of licorice extract every year However, due to the fact that Azerbaijan, Uzbekistan, Afghanistan and other Central Asian countries take licorice cultivation and export as a new industry strongly supported, and the gradual depletion of China's wild licorice resources, China's export of licorice to the United States only accounts for 15% of the imported licorice in the United States Japan is the main export market of Glycyrrhiza in China for a long time, which imports about 1 / 3 of Glycyrrhiza in China every year; China exports 40% of Glycyrrhiza to the United States and 20% to the European Union.