Interaction between Schisandra chinensis and chemicals
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Last Update: 2020-04-03
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Source: Internet
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Author: User
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2015-12-11 classification: efficacy effect: 0 people comment on Schizandra chinensis (Turcz.) Baill Lignans containing several dibenzo cyclooctadiene types have inhibitory effects on the absorption of rhodamine 123 in Caco 2 cells and P-gp-mediated transport of digoxin and rhodamine 123 Cell test showed that most lignans could slightly or moderately increase the absorption of rhodamine 123, among which deoxyschisandrin, angelica acylmicin, gomicin a, tiegeoylmicin h and gomicin C had significant effects, and had a concentration related mouth In the Caco-2 cell experiment, the compounds increased the concentration of digoxin Papp A-B and decreased Papp b-a When Schisandra chinensis is taken orally together with drugs with P-gp substrate properties, it may increase the intestinal absorption of the latter or increase their bioavailability
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