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Int J Urol: How long should a patient be observed after radical prostatectomy?

 Last Update: 2022-03-04
 Source: Internet
 Author: User

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PCa is the second most common cancer in men worldwide
.

There are several approaches to radical resection of PCa, including retropubic radical prostatectomy, LRP, or robotic-assisted LRP

Recently, researchers from Japan, published in "Int J Urol", investigated PSA failure and other causes by using Weibull analysis since there is currently no recommended observation period for patients undergoing radical prostatectomy.
The risk rate of death to determine the postoperative observation time
.

Postoperative observation time was determined by investigating the risk rate of PSA failure and death from other causes using Weibull analysis observation time

The study included 612 patients who underwent laparoscopic radical prostatectomy between June 2002 and December 2017
.

According to the D'Amico risk classification, the researchers divided patients into three age groups: <60 years, 60-69 years and ≥70 years

The findings found that the risk rate of death from other causes increased over time in all age-disaggregated groups
.

In contrast, the risk rate of PSA failure gradually decreased

Age group ≥70 years showed highest risk rate Age group ≥70 years showed highest risk rate of PSA failure Highest risk rate of PSA failure in high-risk group Highest

Optimal observation time after LRP

In conclusion, observation time after laparoscopic radical prostatectomy can be assessed by comparing estimated risk rates for PSA failure and death from other causes based on Weibull analysis
.

Urologists should pay attention to age and risk classification for optimal postoperative observation

Observation time after laparoscopic radical prostatectomy, which can be assessed by comparing estimated risk rates for prostate-specific antigen failure and death from other causes based on Weibull analysis Estimated risk rates for specific antigen failure and death from other causes to assess

Original source:

Masanori Hasegawa, Koichiro Yamada, Keisuke Shigeta et al.

How long should urologists observe patients with prostate cancer after radical prostatectomy? Weibull analysis left a message here

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