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    Home > Biochemistry News > Biotechnology News > Instructions for use of sterile swab tubes

    Instructions for use of sterile swab tubes

    • Last Update: 2022-08-30
    • Source: Internet
    • Author: User
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    In daily environmental monitoring, the contact dish method and the cotton swab method are common methods for surface microbial monitoring of aseptic production of pharmaceutical products, which are recommended and introduced in the current European and American GMP guidelines.


     

     

    Here's how to use a sterile swab tube:

     

     

    11.


     

    • The product is in three-layer aseptic packaging.


       

      2.


       

      • The product is in three-layer aseptic packaging.
        During the process of entering the clean area, with the improvement of the cleanliness level, the plastic outer packaging can be removed layer by layer
        .
      • After unscrewing the cap, ensure that the solution wets the swab tip, contact the sampling surface at an angle of about 30°, and wipe slowly and thoroughly
        .
        Moving it from side to side while moving forward, the wiping process covers the entire coated area
        .
        Then turn the cotton swab over, and let the other side of the cotton swab also wipe, the wiping direction is perpendicular to the previous wiping direction (as shown in the figure below)
        .
        (Note: Use the same force, wipe speed, and wipe path as possible for each sample
        .
        )
      • Swab 25 square centimeters in the sampling area
        .
        The swab tip is spread evenly on the surface of a dish with sterile medium such as TSA
        .
      • Place the plate directly in the incubator
        .
        Dispose of the used swab tube for waste disposal
        .
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