Innovation is the foundation for pharmaceutical enterprises to keep ahead

Internationalization of local enterprises is becoming a new development trend of pharmaceutical enterprises As one of the top 100 pharmaceutical enterprises and influential pharmaceutical enterprises in China, Yabao pharmaceutical industry has been committed to scientific and technological innovation in recent years, and has obtained a series of important achievements It has transformed from a simple drug manufacturer for children to a drug manufacturer for cardio cerebrovascular and tumor, among which scientific and technological innovation plays a decisive role In May of this year, Dr Wang Peng, a special expert of China's "thousand talents plan", who was hired by yabaohua to be a returnee with international experience and initiated a new path of pharmaceutical research and development in China, presided over the work of Yabao Pharmaceutical Research Institute Wang Peng's whereabouts have always been sought after by the pharmaceutical industry, and what kind of changes he will bring to Yabao has attracted the attention of the industry For this reason, the reporter of science and technology daily interviewed him in Beijing Yizhuang Development Zone, and the two sides made in-depth discussion on the innovation and development of pharmaceutical enterprises Innovation is a state that cannot be surpassed What do you think is the essence of scientific and technological innovation? As a pharmaceutical enterprise, what should be the focus of scientific and technological innovation? Wang Peng: I think the essence of innovation is to master the core technology and independent intellectual property rights, promote the continuous optimization and upgrading of industrial structure, and promote the sustainable development of social productivity Science and technology innovation is a systematic project, which includes knowledge innovation, technology innovation and management innovation led by modern science and technology Pharmaceutical enterprises are high-tech enterprises, which focus on the innovation of R & D technology, R & D concept, R & D strategy and, of course, R & D management Q: what is the significance and unique value of scientific and technological innovation for enterprises? Wang Peng: enterprise development depends on science and technology, and science and technology development depends on innovation Continuous innovation is the soul and theme of contemporary science and technology development Only with the support of innovative technology, can a pharmaceutical enterprise always be in the leading position in the fierce market competition Innovation is a state that is often imitated but never surpassed Without core technology and independent intellectual property rights, there will be no independent innovation ability and no initiative for future development Only by comprehensively improving the independent innovation ability, enhancing the independent development ability and mastering the independent intellectual property rights, can the enterprise improve its competitiveness and anti risk ability; only by truly mastering the core technology, can it seize the commanding point of science and technology, occupy a seat in the domestic and international high-tech field, and the enterprise can be full of vitality Therefore, scientific and technological innovation is the key to the success of pharmaceutical enterprises and the decisive factor for the development of enterprises Q: why is the implementation of scientific and technological innovation talents the key? How does Yabao pharmaceutical absorb and retain scientific and technological talents? What is the current situation of scientific and technological talents in enterprises? Wang Peng: the reason why I was employed by Yabao Pharmaceutical Group is that I saw that Yabao keeps innovating in the concept of talent management and has established a good incentive mechanism: first, it guarantees the R & D investment from the system At present, the annual investment has reached more than 5% of the sales revenue, and the basic conditions of R & D have been constantly improved The second is to implement a reasonable salary incentive mechanism for the core scientific and technological talents, enhance the innovation power of the scientific and technological talents, and promote the efforts of the core scientific and technological talents to be consistent with the overall goal of the enterprise Third, it has established a normal training mechanism and cultivated high-level scientific and technological talents for enterprises Fourth, establish a reasonable promotion mechanism In addition to ensuring the salary and learning opportunities of core technology talents, Yabao also provides corresponding promotion space for core technology talents to encourage them to lead the innovation work of R & D team at a higher level At present, Yabao has established research institutions such as national recognized enterprise technology center, National Postdoctoral research workstation, Yabao Pharmaceutical Group sub center of National Engineering Center for pharmaceutical preparations, academician workstation of Shanxi Province, Yabao pharmaceutical graduate education innovation center of Shanxi Province, Taiyuan biomedical research and development center, forming a three-dimensional R & D network system and building drug R & D and production We have set up an international team of innovative talents Re layout of new drug development strategy: what is the focus and direction of Yabao's new product research and development? What are the prospects and advantages of such a development strategy? Wang Peng: Yabao's scientific and technological R & D innovation focuses on three major areas: Pediatrics, cardio cerebrovascular disease and tumor drug use (that is, taking pediatrics as the main drug and gradually developing to cardio cerebrovascular disease, tumor and other drugs) Yabao has established a new product R & D focus on Modern Chinese medicine, chemical drugs, 24-hour slow and controlled-release agents and biological agents, assisted by health food and supplemented by health products The strategic pattern of new products Dinggui'er umbilical patch, a big brand of children's medicine, is Yabao's fist product It has been accepted by the market and clinical medicine for nearly 20 years, making Yabao known as "expert of children's medicine" Therefore, the development of paediatric drugs, the second development of large varieties, and technology upgrading have irreplaceable development advantages However, the drug demand for cardiovascular and cerebrovascular chronic diseases is wide, and the clinical demand for tumor drugs is also large, which is the direction of our research and development Such a development strategy is scientific, in line with market demand, reflecting the advantages of enterprises, so it has a good prospect Q: how do you think an enterprise should keep technological innovation and constantly improve the level of achievement transformation? Wang Peng: Yabao has remarkable points in continuous innovation, mainly in three aspects: first, innovation of R & D strategy On the one hand, from domestic generic drugs to the combination of domestic generic drugs and international high-end generic drugs, improve the accessibility of Chinese patients to high-quality and high-quality generic drugs and participate in international competition On the other hand, the second development and upgrading of existing preparations and large varieties will further meet the market demand On the other hand, through international cooperation, research and development of innovative drugs will be carried out The innovation of R & D strategy is to maintain the leading position of Yabao in China Second, innovation of R & D concept Yabao adheres to the combination of long-term R & D and short-term imitation, strengthens the scientificity of new product project approval, speeds up the R & D speed, pays attention to process design, improves the R & D quality, strengthens the pilot test and process verification, promotes the transformation of scientific and technological achievements, strengthens the protection of intellectual property rights, and improves the ability of independent innovation; strengthens the technical upgrading and secondary development of existing advantageous products, builds technical barriers, and forms Differentiation of competitive advantage pattern, improve the core competitiveness R & D concept innovation is to ensure the sustainable development of Yabao Third, innovation of R & D technology Through international cooperation, we should firmly grasp the core technology, improve the scientific and technological level of the enterprise, and enhance the self-confidence of the enterprise Q: what achievements has Yabao made in scientific and technological innovation in recent years? What are the main aspects? Wang Peng: at present, there are more than 520 new products developed by Yabao Pharmaceutical Co., Ltd., of which more than 420 have been put into production At the same time, 51 Pharmaceutical Invention patents, 127 design patents, 31 authorized invention patent certificates and 115 design patent certificates have been applied to the State Intellectual Property office 283 registered trademarks and 66 trademark certificates have been applied to the State Administration for Industry and commerce There are nearly 100 scientific research projects under research and 12 provincial and ministerial level scientific and technological support projects The indications of the research project are concentrated in the three characteristic fields of Pediatrics, cardio cerebrovascular disease and tumor medicine, with prominent advantages in dosage forms, including modern dosage forms such as cataplasm, transdermal patch, sustained and controlled-release preparation, nano preparation, liposome, etc., advanced equipment, online quality control in the whole production process, and expected to be put into production in recent years Internationalization brings a new starting point: as an important development strategy of Yabao, what is the relationship between international projects and technological innovation? Wang Peng: international projects are one aspect that can particularly reflect the ability of scientific and technological innovation This aspect is diversified Its connotation refers to the development, registration, production, marketing (trade) of international cooperative innovative drugs and international high-end generic drugs Among them, the development and independent research and development of international cooperative innovative drugs and international high-end generic drugs have elements of scientific and technological innovation, but the only difference is the way of research and development To carry out international projects and cooperate with advanced enterprises in developed countries in Europe and the United States will bring new ideas, new perspectives and new vitality to Yabao, while to carry out the research and development of international innovative drugs and generic drugs will bring Yabao to a new starting point and new height of scientific and technological innovation Q: what are Yabao's plans for independent innovation, joint development and cooperation with foreign countries in the future? Wang Peng: Yabao will adhere to the principle of independent research and development, combination of external cooperation and development, combination of long-term research and development and short-term imitation in scientific and technological innovation In terms of independent research and development, the development of chemical generic drugs will change from domestic market to both international and domestic market At present, the group has established 8 R & D platforms, including innovative traditional Chinese medicine, chiral synthesis and resolution of chemical APIs, oral sustained-release preparations, oral osmotic pump controlled-release preparations, long-term microsphere injection, etc In terms of joint development, we should establish a technological innovation system with enterprises as the main body, market as the guide and the combination of production, learning and research, so as to form a long-term competitive advantage of enterprises In terms of international cooperation, it will also strengthen cooperation with multinational companies, top foreign academic teams or some small companies to develop innovative drugs.