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    Home > Biochemistry News > Plant Extracts News > Inferring Biological Functions of Guanylyl Cyclases with Computational Methods

    Inferring Biological Functions of Guanylyl Cyclases with Computational Methods

    • Last Update: 2020-11-15
    • Source: Internet
    • Author: User
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    A number of studies have shown that functionally related genes are often co-expressed and that computational based co-expression analysis can be used to accurately identify functional relationships between genes and by inference, their encoded proteins. Here we describe how a computational based co-expression analysis can be used to link the function of a specific gene of interest to a defined cellular response. Using a worked example we demonstrate how this methodology is used to link the function of the Arabidopsis
    Wall-Associated Kinase
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    gene, which encodes a functional guanylyl cyclase, to host responses to pathogens.
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