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In addition to "caution in elderly patients", famotidine also has these precautions!

 Last Update: 2023-01-06
 Source: Internet
 Author: User

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What are the common drugs for the digestive system? Search for "evidence-based medicine" to find out!

Famotidine is a histamine 2 (H2) receptor antagonist widely used in digestive tract diseases
such as peptic ulcer, heartburn, and acute gastric mucosal lesions.

In terms of medication safety, in addition to the cautious use of the elderly, you should also pay attention to these precautions!

Liver and kidney insufficiency should be used with caution (1) This product should not be used continuously for more than 7 days, and the symptoms are not relieved, and a doctor or pharmacist should be
consulted
。
(2) Please consult a doctor or pharmacist
for children's dosage.

(3) Patients with hepatic insufficiency and children should be used
with caution.

(4) This product is mainly excreted by the kidneys, and patients with renal insufficiency should be used
with caution.

(5) If you overdose or have serious adverse reactions, you should seek medical attention
immediately.

(6) Those who are allergic to this product are banned, and those who are allergic should use
with caution.

(7) It is forbidden to use
this product when the properties change.

(8) Keep this product out of
reach of children.

(9) This product will have hidden gastric cancer symptoms, so it should be administered
after excluding tumors and esophageal and gastric varices.

(10) In the process of treatment, full observation should be carried out, and the minimum use of treatment limited to treatment according to the condition (invasive stress response is about 3 days, others are about 7 days), in addition, attention should be paid to observing blood images, liver function, etc.
[1-11].

Central nervous system adverse reactions
Older patients treated with famotidine tablets and patients with moderate to severe renal impairment have experienced central nervous system (CNS) adverse effects
including confusion, delirium, hallucinations, disorientation, agitation, seizures, and lethargy.
Since the plasma concentration of famotidine in patients with impaired renal function is higher than in patients with normal renal function, it is recommended to adjust the dose
in patients with renal impairment.

Complicated by gastric malignancy
In adults, famotidine can conceal the symptomatic response
of gastric malignancies.
If famotidine is not effective or recurs with early symptoms, a diagnosis of gastric malignancy is indicated [12][14].

What other drugs are available for peptic ulcers? How to deal with drug overdose?

More commonly used drugs for the digestive system, on "clinical decision-based medicine" you want to see, here are all! 👇

References [1] American Geriatrics Society Beers Criteria Update Expert Panel:American Geriatrics Society 2019 updated AGS Beers Criteria（R）for potentially inappropriate medication use in older adults.
J Am Geriatr Soc 2019; 67（4）:674-694.
[2] Drug information: Famotidine tablets, Harbin Pharmaceutical Group Sanjing Qianhe Pharmaceutical Co.
, Ltd.
, Sinopharm Quasi-word H20093044 [3] Drug information: famotidine tablets, Jiangsu Hengrui Pharmaceutical Co.
, Ltd.
, Sinopharm H32023658 [4] Drug information: Famotidine chewable tablets, Guangzhou Bossero Pharmaceutical Co.
, Ltd.
, Sinopharm H20041793 [5] Drug information: famotidine capsules, Sinopharm Shantou Jinshi Pharmaceutical Co.
, Ltd.
, Sinopharm H20023398; 2015/11/30.
[6]Drug information: famotidine dispersible tablets, Sichuan Qili Pharmaceutical Co.
, Ltd.
, Sinopharm H20030538; 2013/12/19.
[7]Drug information: famotidine granules, Zhejiang Yadong Pharmaceutical Co.
, Ltd.
, Sinopharm H10950256; 2007/04/18.
[8]Drug information: famotidine injection, Zhejiang Zhenyuan Pharmaceutical Co.
, Ltd.
, Sinopharm H20046639; 2015/12/01.
[9] Drug information: famotidine granules, Sinopharm Rongsheng Pharmaceutical Co.
, Ltd.
, Sinopharm H20033269 [10] Drug information: Famotidine for injection, Shanxi Kangbao Biological Products Co.
, Ltd.
, Sinopharm H10970269; 2013/12/05.
[11] Drug information: Famotidine for injection, Yamauchi Pharmaceutical Co.
, Ltd.
, Yamanouchi Pharmaceutical Co.
, Ltd.
, Sinopharm J20030014 [12]Product Information:FAMOTIDINE tablet，Alembic Pharmaceuticals Inc.
，Updated October 4，2021.
[13]Product Information:FAMOTIDINE-famotidine injection，solution，Fresenius Kabi USA，LLC，Updated May 10，2021.
[14]Product Information:FAMOTIDINE powder，for suspension，Zydus Pharmaceuticals USA Inc.
，Updated April 22，2021.
[15]Product Information:FAMOTIDINE powder，for suspension，Hi-Tech Pharmacal Co.
，Inc.
，Updated October 2，2020.
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