Important research results interpret the new progress of dementia research!

In this paper, I have compiled several important research results, and jointly interpreted the new achievements of scientists in the field of dementia research, and shared them with you! Photo source: cc0 public domain [1] neurology: identification of inflammatory markers related to dementia doi: 10.1212/wnl.0000000000008682 Recently, in a research report published in the international journal Neurology, scientists from the University of Texas Health Science Center found that the inflammatory marker sCD14 was directly related to brain atrophy, cognitive decline and dementia This study is based on two large community-based heart studies involving 4700 participants, researcher Sudha According to Seshadri, sCD14 may be a useful marker for assessing the risk of cognitive decline and dementia in individuals, and what excites researchers most is that if there is time to intervene or change a person's life process, they may be able to assess their risk in advance 【2】 CIA: Tai Chi may benefit dementia patients doi: 10.2147/cia.s228931 recently, an international journal, clinical interventions in In the Research Report on aging, scientists from the University of Bournemouth in the UK found that Taiji can bring positive health benefits to patients with Alzheimer's disease; in the article, researchers wanted to study whether Taiji can benefit dementia patients, especially whether Taiji can prevent their falls and improve their quality of life Dr Samuel Nyman, researcher, said that we are very interested in studying whether Taiji can improve the body balance of dementia patients and effectively prevent their falls, which is very important, because the risk of falls in dementia patients is twice that of normal people, and the risk of falls and injuries is twice that of normal people In this paper, the researchers selected a group of people who can carry out normal activities as the control group, and compared it with the experimental group who has carried out Taiji activities for six months; the results show that those who can follow the Taiji program can maintain a good quality of life, while the control group has a decline in the quality of life in the same period The researchers said that those who take Taiji do like these courses very much, and they will meet with people who have dementia and need family care; Taiji is a very safe and gentle way of exercise, and many family nurses are very willing to support their relatives to keep healthy through classroom and family contact; although the researchers found that the test scores of the crowd were not However, the tendency of Taiji to prevent falls is obvious 【3】 Neurology: it's terrible to be illiterate! The risk of dementia in illiterate people is three times higher than in the normal population! doi：10.1212/WNL.0000000000008587 Recently, in a research report published in the international journal Neurology, scientists from Columbia University and other institutions found that the risk of dementia among illiterate people (people who have never learned to read or write) is nearly three times higher than that among people with literacy; according to the statistics of the U.S Department of education, there are about 32 million illiterate people in the United States Researcher Jennifer J Manly said that having reading and writing ability can help people to participate in more brain using activities, such as reading newspapers, helping children and grandchildren to guide homework, etc.; previous research results showed that such activities can reduce the risk of dementia in individuals In this study, we provide evidence that reading and writing may be an important factor to help maintain a healthy brain 【4】 JAMA psych: 82000 people over 50 years of research results show that teenagers' personality or the risk of dementia in later life doi: 10.1001/jamapsychiatry.2019.3120 can a person's personality in youth predict the risk of dementia 50 years later? Recently, in a research report published in the international journal JAMA psychiatry, scientists from institutions such as the University of Rochester found that those calm, mature and energetic high school students tend to have a lower risk of dementia in later stage Researchers Kelly Peters said that staying calm and mature in adolescence was directly related to a 10% reduction in the risk of dementia in adulthood The findings come from a personality test conducted in the 1960s on about 1200 82000 high school students in the United States More than 50 years later, the researchers compared the personality characteristics of these participants with the diagnosis of dementia Conduct relevance study A large amount of research evidence shows that personality changes before and after individuals are diagnosed with dementia Researchers do not know whether personality or personality problems really lead to dementia? In this study, the average age of participants was 16 years old, and the researchers assessed 10 characteristics, including calmness, vitality, organization, self-confidence, maturity / responsibility, leadership, impulse, desire for social interaction, social sensitivity, and artistic and intellectual well-being; between 2011 and 2013, when the age of participants was about 70 years old, more than 2500 people suffered from dementia Dementia [5] neuron: a new mode of dementia spreading in brain neural network doi: 10.1016/j.neuron.2019.08.037 In a new study, scientists at the University of California, San Francisco, used brain Connection maps to predict the spread of brain atrophy in patients with frontotemporal dementia (FTD) They provide new evidence that the loss of brain cells associated with dementia is spread through a network of brain cells established by synaptic connections The results improve scientists' understanding of how neurodegenerative diseases spread, and help to develop new therapies and new assessment methods to effectively alleviate the deterioration of such diseases Our research reveals how dementia spreads, opening up a window into the biological mechanism of the disease, which can find the most vulnerable parts of our brain cells or neural circuits, the researchers said FTD is the most common type of dementia in people under 60 years old Its symptoms are reflected in language and behavior As with Alzheimer's disease, the diversity of FTD symptoms reflects a significant difference in the diffusion pattern of neurodegenerative diseases in patients' brains This difference makes it difficult for scientists to find drugs to solve brain atrophy, or to carry out clinical trials to evaluate whether a new treatment can effectively prevent the deterioration of the disease Photo source: University of aberty Dundee [6] SSH: only two minutes of exercise a week can effectively reduce the risk of dementia in the elderly doi: 10.1007/s11332-018-0498-2 recently, an international journal Sport Sciences for In the report on health, scientists from the University of Aberdeen found that for people over 60 years old, just two minutes of exercise a week can reduce their risk of age-related diseases such as dementia In this study, the researchers recruited 17 participants aged 60-75 to study, and trained them twice a week for 10 weeks; participants were required to carry out so-called sit (sprint interval At the same time, they were asked to ride on a fixed bike for as long as 6 seconds before rest, and then participants repeated the exercise process until they were able to complete one minute of high-intensity exercise at each stage 【7】 Ijgp: migraine or closely related to high-risk dementia doi: 10.1002/gps.5180 recently, an International Journal of geriatric psychology was published with the title of "migrate and the risk of all ‐ cause demantia, Alzheimer's disease, and vascular demantia: a prospective cohort study in community ‐ dwelling older In their study, scientists from the University of Waterloo found that migraines are either closely related to high-risk dementia Dementia is the most common neurological disease in the elderly, and headache, including migraine, is the most common neurological disease in all age groups In this study, researchers studied 679 community residents aged 65 and above, who showed that migraine is an important risk factor for dementia in the population, including Alzheimer's disease And so on 【8】 Neurosycologia: new research helps early diagnosis of dementia doi: 10.1016/j.neurosycologia.2019.04.007 according to the latest research of the University of Arizona and Baycrest Health Science Center of the University of Toronto, scientists may have found early detection methods for some forms of dementia According to a study published in the Journal Neuropsychologia, patients with rare neurodegenerative brain disease (called primary progressive aphasia, or PPA) show abnormal brain function in areas that appear to be structurally normal on MRI scans We wanted to study how degeneration affects brain function, the researchers said The brain has yet to show functional defects in areas of structural damage on MRI Structural MRI provides three-dimensional visualization of brain structure, which is useful in studying patients with diseases that cause brain cells to disappear, such as PPA On the other hand, magnetoencephalogram (or MEG) "gives a really good spatial accuracy about the source of brain response We want to know whether the reduced brain function comes from the atrophic area or from the early stage The senior author of the study, Jed Melzer, an assistant professor of psychology at the University of Toronto, said 【9】 Alzheimer's: brain healthy diet may reduce the risk of dementia in the population doi: 10.1016/j.jalz.2018.12.011 recently, an international journal Alzheimer's& In the Research Report on dementia, scientists from the University of New South Wales found that when people follow a diet that improves brain health, their risk of cognitive impairment will be reduced; the researchers believe that long-term adherence to a diet that increases brain health seems to reduce individual cognitive impairment And related diseases, including Alzheimer's disease and dementia In this paper, the researchers analyzed the "minderanean dash intervention for neurodegenerative delay" Diete, Mediterranean - Deshu intervention neurodegenerative delayed diet) is a potential protective effect Mediterranean diet is considered to have some protective effects on other health aspects, such as cardiovascular disease; the component of mind diet is based on Mediterranean diet, and additionally added food related to brain health This diet is mainly composed of 15 recipes, with emphasis on green Leafy vegetables, whole grains, olive oil and a small amount of red meat 【10】 Keeping active in middle age may be tie to lower risk of dementia According to a study published on February 20, 2019 in the online journal Neurology, the Medical Journal of the American Academy of Neurology, maintaining physical and mental activity in middle age may be associated with a reduced risk of dementia decades later Useful psychological activities include reading, playing musical instruments, singing in a choir, visiting concerts, gardening, doing needlework or attending religious ceremonies The results suggest that these middle-aged activities may be