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*For medical professionals only, multi-pronged
approaches may be more effective
for gout.
Screenshot of the review article
Jaejoon Lee, Sungkyunkwan University School of Medicine, South Korea, said:
.
The researchers used the Cox proportional hazard model to analyze the correlation
between changes in MetS and gout attacks.
Of the 1293166 participants, 18,473 were diagnosed with gout (incidence: 3.
36 per 1000 person-years), the study found:
Jaejoon Lee, Sungkyunkwan University School of Medicine, South Korea, said:
approaches may be more effective
Executive Summary
for gout.
Screenshot of the review article
status quo
Jaejoon Lee, Sungkyunkwan University School of Medicine, South Korea, said:
- The burden of gout is increasing globally, so strategies to prevent the onset of gout are becoming increasingly important
. - MetS is a class of cardiovascular risk factors including abdominal obesity, insulin resistance, hypertension, and hyperlipidemia
.
A high-fat diet and sedentary lifestyle have led to an increased
prevalence of metabolic syndrome. - Recent studies have shown that changes in MetS not only alter the risk of cardiovascular events, but are also associated with
changes in the risk of atrial fibrillation, end-stage renal disease, and all-cause mortality.
However, there is little
data on whether changes in MetS affect gout attacks.
conclusion
.
The researchers used the Cox proportional hazard model to analyze the correlation
between changes in MetS and gout attacks.
Of the 1293166 participants, 18,473 were diagnosed with gout (incidence: 3.
36 per 1000 person-years), the study found:
- Participants with MetS-chronic (MetS at all three health checks) had a nearly fourfold higher risk of gout events than participants without MetS-chronic (no MetS at all three health checks) [aHR (95% CI): 3.
82 (3.
67 to 3.
98)]; - Progress in MetS more than doubled the risk of sudden gout [aHR(95% CI): 2.
31 (2.
20 to 2.
43)]; - However, recovery from MetS was associated with a nearly half risk reduction in the risk of sudden gout compared with MetS-chronic population [aHR(95% CI): 0.
52 (0.
49 to 0.
56)].
prospect
Jaejoon Lee, Sungkyunkwan University School of Medicine, South Korea, said:
- Because recovery from MetS can reduce the risk of gout, it is important to manage MetS in younger men, such as lifestyle changes and appropriate medications
.
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