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bobvila
bobvilaAccording to a new study by researchers from University College London and the London School of Hygiene and Tropical Medicine, the theory that too clean a modern society leads to defective immune systems in children should be overturned .
Childhood ImmunizationIn medicine, the "hygiene hypothesis" states that early childhood exposure to specific microorganisms can prevent allergic diseases by promoting the development of the immune system
.
However, there is a general view that the Western 21st century society is too hygienic, which means that young children and children are less likely to be exposed to bacteria in their early life, and therefore less resistant to allergies
.
.
The prevailing view is that the 21st century society in the West is too hygienic, which means that young children and children are less likely to be exposed to bacteria in their early life, and therefore less resistant to allergies
Keeping clean and sanitary is not contradictory to being in contact with microorganisms in the environment, and to a certain extent, it is beneficial to the immune system
Lead author and Professor Emeritus of Medical Microbiology Graham Rook (University College London Infection and Immunity) said: "Early life exposure to microorganisms is essential for the training of the immune and metabolic system
.
In our intestines, skin and respiratory tract Growing organisms also play an important role in maintaining our health until old age
Infect
But for more than 20 years, there has been a public statement that hand and household hygiene are essential to prevent contact with pathogenic pathogens, but also prevent contact with beneficial organisms
.
In this paper, the researchers set out to reconcile the apparent conflict between the need for cleanliness and the need for microbial contact to build our immune and metabolic systems
.
In reviewing the evidence, the researchers pointed out four factors
.
First of all, the microorganisms found in modern homes are largely not the ones we need for immunity
.
In the presence of toxic molecules, antigens present on the mucosal surface may become allergens
.
Antigens entering the intestine or respiratory tract usually cause tolerance
In the presence of toxic molecules, antigens present on the mucosal surface may become allergens
As a key part of targeted hygiene
Useful and potentially harmful hygiene strategies
Useful and potentially harmful hygiene strategiesProfessor Luke added: “Therefore, cleaning the home is good, and personal cleaning is also good .
However, as explained in detail in the paper, in order to prevent the spread of infection, it is necessary to clean the hands and surfaces that are most frequently involved in the spread of infection.
Cleaning the home is good, and personal cleaning is also good.
Cleaning the home is good, and personal cleaning is also good.
These contacts do not conflict with wise targeted hygiene or cleaning.
These contacts do not conflict with wise targeted hygiene or cleaning.
Microbial exposures that establish immunoregulation are compatible with targeted hygiene.
Microbial exposures that establish immunoregulation are compatible with targeted hygiene.
DOI:https://doi.
org/10.
1016/j.
jaci.
2021.
05.
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