If there are incidental pathological findings in young gynecomastia, should the pathological examination be a routine examination?

Large-scale studies of adult gynecomastia populations have shown that incidental pathological findings have a lower incidence but significantly increase the risk of breast cancer
.
Given the low incidence of breast cancer in this population, pathological examination of breast tissue in young men is controversial

Figure 1 Source of the article

The researchers examined the pathological findings of a large cohort of adolescents with gynecomastia, retrospectively analyzing men who underwent unilateral or bilateral mastectomy for gynecomastia at an institution between February 2007 and November 2019 demographics, medical history, surgical characteristics, and pathological findings to assess the need for routine histological analysis of this population
.

A total of 268 male patients were included in the study
.
The average age was 16.

Table 1 Detailed findings of atypical hyperplastic lesions or ductal carcinoma in situ in young men

Findings that may increase breast cancer risk were found in three male adolescents (1.
2%)
.
The rates of pathological findings with potential increased risk, particularly hyperplasia with atypia and ductal carcinoma in situ, were similar between male and female adolescents

Despite worrisome pathological findings, little is known about the natural history of dysplasia and ductal carcinoma in situ in young men and routine analysis is not recommended

Original article:

Maroney, Jenna, Dannheim, Katelyn, Hollowell, Monica, Labow, Brian, Rogers-Vizena, Carolyn.