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Perhaps the most important question now about COVID-19 is the degree to which the initial infection of the new coronavirus protects against re-infection.
it affects vaccine development and population immunity, which is something we should all consider, and antibody testing is now available.
of this article comes from William Petri, a medical scientist with a Ph.D.
William specializes in internal science, specializing in infectious diseases.
is currently working on a method of COVID-19 vaccination, while also caring for hospitalized patients.
following are William's answers to common questions about testing that can tell you about immunity.
are the different types of 1COVID-19 tests? We've all seen the nasal SWAB test, which is used by 22 million people in the U.S., reflecting whether you're currently infected with the new coronavirus that causes COVID-19.
test to detect the genetic code of the SARS-CoV-2 virus in your body.
if your nasal swab PCR tests positive, it will not only infect you, but may also be contagious and should remain isolated until recovery.
contrary, antibody tests can determine if you have COVID-19 in the past.
it can measure your body's immune response to infection, which can occur within days to weeks of the infection starting.
the antibody can appear after the infection has been eliminated or even when you are infected.
2 immune system cure COVID-19? The answer is yes.
rarely, possibly one percent, the immune system naturally removes SARS-CoV-2 from the body.
This is very encouraging for the development of vaccines, as it should be much easier to produce an effective vaccine than HIV or hepatitis C virus, for example, the immune system often (for hepatitis C) or almost always (for HIV).
SARS-CoV-2 is different from the two viruses because it has a so-called proofing gene that prevents mutations from being introduced during virus replication.
3 antibodies prevent new coronavirus infections? Answer: Probably.
image above shows a molecular model of the binding of type Y antibodies (blue) to the puncture protein (red) of the new coronavirus SARS-CoV-2.
if the antibody binds to the puncture protein region (i.e., the channel that infects human cells), the antibody will prevent infection.
we know that in test tubes, antibodies against the virus can mesothied it.
they prevent viruses from entering human cells and causing infection.
, however, not every antibody can also prevent infection caused by the virus.
the best antibody in the world is an antibody that can bind to the receptacle binding domain of the new crown virus protrusion protein attached to the host cell ACE2 receptacle.
RBD is located at the tip of the spike protein and is the part of the peak that touches ACE2.
the first step of a viral infection, when the coronavirus adheres to a human cell membrane.
4 If my antibody test is positive, am I immune? Answer: Maybe.
the explanation for the positive antibody test is that we don't yet know if antibodies against RBD can make people immune.
we don't know how much of this RBD antibody is needed to ensure protection.
, not all antibody tests against COVID-19 can measure antibodies against RBD.
some tests to measure antibodies against cells entering unwanted parts of the virus.
these antibodies, which are not targeted at RBD, recognize the virus, but do not prevent it from infecting human cells and causing viral infections.
, only antibodies that prevent the hedgehog from connecting to the ACE2 receptured body can guarantee immunity.
only antibody tests that measure the amount of these antibodies can predict immunity.
this summer, when large Phase III vaccine studies begin, we will have a better understanding of the ability of RBD antibodies to prevent infection.
because these vaccines are designed to produce antibodies against RBD.
5 I should have an antibody test? If you're curious about whether you've used COVID-19 in the past, it makes sense to test it.
note that some tests have shown a large number of false positives so far.
if you do have antibodies, don't think you're immune to the new coronary virus.
you may be as susceptible to infection as people without antibodies.
so even if you do have antibodies, it's still critical for all of us to wear a mask indoors and keep your social distance when dealing with the ongoing threat of this pandemic.
: The COVID-19 pandemic is destroying higher education and affecting the job market in unprecedented ways.
we strive not only to provide academic insights into what is happening, but also to provide expert analysis of how the world will change.
Source: Science News Medical Technology Heights Source: Medical Technology Highlands !-- Content Show Ends -- !-- Determines whether the login ends.