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Research shows that the granddaughters and great-granddaughters of men who started smoking before puberty have more body fat than expected
A new study led by the University of Bristol, published today (21 January 2022) in Scientific Reports, reports that women gain more body fat if their grandfather or great-grandfather started smoking before puberty
Experiments in modelling studies elsewhere have shown that exposure of males to certain chemicals before they reproduce can have an effect on their offspring
To investigate the effects of prepubertal smoking in humans, scientists at the University of Bristol looked at the possible effects of ancestral prepubertal smoking on '90s children', a study of more than 14,000 people
Professor Gene Golding, lead author of the study, said: "This study provides us with two important results
If these associations are confirmed in other datasets, this will be the first human study with suitable data to begin investigating these associations and begin to unravel the origin of potentially important intergenerational relationships