Hypertension: The degree of atherosclerosis at the arterial where the pressure receptor is located independently predicts a drop in blood pressure in patients with ischemic stroke

Night blood pressure (BP) usually drops by 10 to 20 percent of daytime levels, and abnormal BP decline may affect vascular health independently of BP levelsThe regulation of BP's decline is involved in arterial pressure-comity reflexes, whose receptors are located mainly in the sinuses of the carotids and the aortic archIn patients with ischemic stroke (IS), the arteries (BRAs) in which these pressure receptors are located are frequently atherosclerosis and may impair their BP regulationIn a recent study published in the journal Hypertension, the cardiovascular authority, researchers looked at the association between BRA atherosclerotic sclerosis and BP decline in IS patientsresearchers measured the incidence of BP decline in subjects on the sixth day of IS through 24-hour dynamic blood pressure monitoring, and scanned the angiography by computer to rate the atherosclerosis of 10 cervical sinuses and aortic arch sections and aggregated it into bra's total atherosclerotic burden78.0% of 245 IS patients had ATHerocytosaBRA's total AS burden and systolic pressure reduction rate (r-0.331; P (0.001) and diastote pressure drop rate (r-0.225; P 0.001) is negatively correlatedAfter adjusting for age, sex, vascular risk factors, 24-hour BP average, cervical artery and intracranial atherosclerosis score, there was still a negative correlation (with adjusted beta of -0.259 (95% CI of -0.416 to -0.102) and adjusted beta at -0.178 (95% CI -0.346 to -0.010) respectively)in general, BRA's higher atherosclerosis burden was associated with a more moderate and independent decline in systolic and diastolic pressure in IS patientsBRA's total atherosclerosis burden may be important for predicting and treating BP decline in IS patients