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Article source: Medical Rubik's Cube Info
Author: Sunshine
On September 23, the CDE official website showed that the Hutchison Whampoa HMPL-760 capsule clinical trial application was approved by the Food and Drug Administration for the treatment of B-cell non-Hodgkin's lymphoma
HMPL-760 is a research, highly selective, third-generation small molecule BTK (Bruton's tyrosine protein kinase) inhibitor that is more effective than the first-generation BTK inhibitor.
BTK is an important signal molecule in the B cell receptor pathway.
At present, five BTK inhibitors have been approved for the market worldwide, namely ibrutinib, AstraZeneca's acatinib, zebutinib, tirabrutinib, and abutinib