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    Home > Medical News > Medical Science News > Humans are more susceptible to cardiovascular disease

    Humans are more susceptible to cardiovascular disease

    • Last Update: 2020-12-26
    • Source: Internet
    • Author: User
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    are more susceptible to cardiovascular disease than other mammals. A genetic inercession of a human ancestor may be the "main culprit" for the risk of cardiovascular disease, U.S. researchers report in the Proceedings of the National Academy of Sciences.
    previous studies have found that cardiovascular diseases such as atherosclerosis are extremely rare in other mammals. For example, captive chimpanzees also have similar risk factors to humans, such as high blood lipids, high blood pressure, and lack of exercise, but chimps rarely suffer from cardiovascular disease, even if they have a heart attack, caused by myocardial scarring and other physical lesions.
    at the University of California, San Diego, fed two groups of mice on a high-fat diet and observed their atherosclerosis. A group of mice had the same CMAH mutation gene as humans, which causes the body to lack a sugar molecule called N-hydroxyacetyl neuraline. The control mice retained the normal CMAH gene.
    found that mice with CMAH mutations nearly tripled their atherosclerosis after being fed a high-fat diet. It also helps explain that even vegetarians are at significantly higher risk of cardiovascular disease than other mammals because of this genetic defect in humans.
    for meat-eating humans, the risk of cardiovascular disease is higher than for vegetarians. The researchers explained that this is because meat contains N-hydroxyacetyl celine, which humans eat as an alien molecule, thus triggering a targeted immune response, and constantly produce antibodies that lead to inflammation, which plays an important role in the occurrence and development of atherosclerosis. In contrast, other mammals have such molecules naturally present in their bodies, and even carnivores do not trigger these immune responses. (Source: Xinhua News Agency)
    relevant paper information: 
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