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Huahai Pharmaceutical's subsidiaries Huaaotai Bio and Huabo Bio HB0028 Injection were approved for clinical use

 Last Update: 2022-05-28
 Source: Internet
 Author: User

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Recently, Huaaotai Bio and Huabo Bio, the subsidiaries of Huahai Pharmaceutical, received the "Drug Clinical Trial Approval Notice" approved and issued by the State Drug Administration for HB0028 injection

HB0028 is a bispecific antibody targeting programmed death ligand 1 (PD-L1) and transforming growth factor-beta (TGF-beta)

In addition, the HB0028 project fused the TGF-β type II receptor with the C-terminus of the anti-PD-L1 antibody, which overcomes the problem that the fusion of the TGF-β type II receptor with the N-terminus of the anti-PD-L1 antibody is prone to produce O sugars.

At present, there are no similar drugs targeting both PD-L1 and TGF-β on the market

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