How to detect systemic lupus erythematosus early

Lead

Lupus erythematosus is not without traces, persistent fever, hair loss, joint pain, facial erythema is often an early manifestation of lupus, when the above symptoms occur, you must be vigilant and seek medical attention
in time.

When lupus erythematosus appears in the early stage, the body generally has four more obvious changes, if you usually observe carefully, you may be able to take treatment as soon as possible, will not further worsen the condition, and can also reduce the pain
of patients.

Four abnormalities in the body when lupus erythematosus appears

1.
Changes in body temperature

When lupus erythematosus appears, fever occurs frequently, and there are many causes of fever, and most people may not pay too much attention
.
However, fever caused by lupus erythematosus is usually caused by the body's immune function, which causes some inflammation
to occur.
With the development of the disease, a persistent low-grade fever will slowly appear, if there is an unexplained fever for a long time, you must be cautious, it is recommended to go to the hospital for a comprehensive examination
as soon as possible.

2.
Joint pain

When lupus erythematosus appears, joint pain may occur, and some patients will experience swelling and pain
in the joints of the hands and feet and ankles in the early stage.
When this pain occurs, everyone may immediately think that it is just the wind cold, so it is easy to confuse
the two.
However, it is important to be vigilant for lupus erythematosus when joint pain occurs to avoid delaying treatment
.

3.
Hair loss

When it comes to hair loss, many people may feel that it is not a big deal, it may be caused by normal stress, or some congenital genetic factors, and will not be taken to heart
.
Lupus erythematosus is usually hidden in the scalp and is difficult to be found, if you do not pay attention for a long time, hair loss will occur, and the problem of hair loss will only be more serious than once, and it is a large area of hair loss, and in severe cases, there may be redness or blisters
.
Therefore, the problem of hair loss cannot be underestimated, and serious cases will affect people's daily life
.

4.
Redness on the face

The appearance of red spots on the face is a typical condition of lupus erythematosus, which occurs in most people who have lupus
.
The surface of the skin usually has skin damage problems, some scales, etc.
, and the red spots on the face become redder in the sun, and the skin problems will become more serious
.
Therefore, this phenomenon should seek medical attention in time, do not treat it as a general skin disease and apply some ointment casually, so as not to delay the condition
.

Lupus erythematosus (LE) is a typical autoimmune connective tissue disease, more common in women
aged 15~40.
Lupus erythematosus can be divided into subtypes
such as discoid lupus erythematosus (DLE), subacute cutaneous lupus erythematosus (SCLE), systemic lupus erythematosus (SLE), deep lupus erythematosus (LEP), neonatal lupus erythematosus (NLE), and drug-induced lupus erythematosus (DIL).

Discoid lupus erythematosus: mainly invades the skin and is the lightest type of
lupus erythematosus.
A few have mild visceral damage that transforms into systemic lupus erythematosus
.
Skin lesions begin as one or several bright red spots, mung bean to soybean large, with adhesive scales on the surface, then gradually enlarge, round or irregular, and the marginal pigment is significantly deepened, slightly above the center
.
The central color is light, can be atrophied, low-lying, and the entire lesion site is discoidal, so it is called discoid lupus erythematosus
.
Damage is mainly distributed in sun-exposed areas, such as the face, ear chakra and scalp, and a few can affect the upper chest, back of the hands, forearms, lips and oral mucosa
.
Most patients have no symptoms of skin lesions, but they are difficult to resolve
completely.
The damage can be distributed symmetrically or fused into pieces, and the damage in the middle of the face can be fused into a butterfly shape
.
Discoid lesions worsen
with sun exposure or exertion.
Damage on the scalp can cause permanent hair loss, and a few old lesions can progress to squamous cell carcinoma
of the skin.

Subacute cutaneous lupus erythematosus: clinically less common, a special intermediate type
.
There are two kinds of skin lesions, one is annular erythema, manifested as single or multiple scattered erythema, ring-shaped, semi-annular or multi-ring, dark red edges slightly edematous and bulging, outer edge with redness, central subsidence with pigmentation and telangiectasia, more likely to occur on the face and trunk; The other type is papulosquamous, with lesions that mimic psoriasis, with erythematous, papular rashes and visible scales on the surface, mainly on the upper extremities of the trunk and face
.
Both lesions usually exist separately, but a few can coexist
.
Skin lesions often recur, the vast majority of patients have visceral damage, but severe cases are rare, mainly manifested as arthralgia, muscle pain, repeated low-grade fever, a few nephritis, blood system changes
.

Systemic lupus erythematosus: Systemic lupus erythematosus is the most severe of
the types.
The vast majority of patients present with multiple systemic lesions, and a minority develop from other types of lupus erythematosus
.
Some patients are also accompanied by other connective tissue diseases, such as scleroderma, dermatomyositis, Sjogren's syndrome, etc.
, forming various overlapping syndromes
.
The clinical manifestations of systemic lupus erythematosus are diverse, complex, and severe
.
Lupus nephritis, lupus encephalopathy, and long-term heavy drug use can be life-threatening
.

Deep lupus erythematosus: also known as lupus panniculitis, it is also an intermediate type of lupus erythematosus
.
Skin lesions manifest as nodules or plaques located deep in the dermis or subcutaneous adipose tissue, of varying size, number, normal or reddish skin color, firm texture, and no movement
.
Damage can occur anywhere, most commonly on the cheeks, buttocks, arms, and to a lesser extent on the calves and chest
.
It can last for months to years, and there is skin atrophy and depression
after healing.
Deep lupus erythematosus may exist alone, transform into discoid lupus erythematosus, or systemic lupus erythematosus, or coexist
with them.

Neonatal lupus erythematosus: manifested as annular erythema of the skin and congenital heart block, self-limited, generally subsiding spontaneously within 4~6 months after birth, but heart disease often persists
.

Drug-induced lupus erythematosus: mainly manifested as fever, arthralgia, muscle pain, facial butterfly erythema, mouth ulcers, and serositis
.
ANA, anti-histone antibodies, anti-ss-DNA antibodies, etc.
are positive
.
After stopping the drug, it gradually improves, and those with more severe disease can be given appropriate amount of glucocorticoid therapy
.