-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory connective tissue disease involving multiple organs [1].
I believe that everyone is familiar with this sentence, it will appear in almost every SLE disease science, and it is this sentence that completely explains why the same SLE diagnosis has very different performance
.
At the same time, different disease manifestations also affect different review items and cycles
.
Doctors often use these review items to determine two key questions about SLE: Is it active? What are the side effects of treatment? Simply put: review is an important means to
judge the condition of SLE.
Double-check, check what
1.
Check according to clinical manifestations
For SLE, the purpose of review is to observe the development of the disease, determine whether it is in the active phase of the disease, and which indicators have recovered [2].
Generally, it includes blood drawing and urine, mainly for blood analysis, blood lipids, erythrocyte sedimentation rate, C-reactive protein, urinalysis, etc
.
Based on the performance of these items, combined with the results of previous tests, doctors can know the extent of
the current condition.
For example, blood analysis tests showing that hemoglobin is higher than before, indicating that the blood damage has recovered to a certain extent; The proteinuria in urinalysis changed from "+++" to "+", indicating that kidney damage has been recovered to a certain extent.
.
.
Every 6 months, immunological tests may be required, mainly including complement, antinuclear antibodies, anti-ENA antibodies, immunoglobulins, etc
.
For example, a decrease in the titter of ds-DNA antibodies indicates that the disease tends to improve
.
2.
Check according to the side effects of drugs
As the saying goes: "It is medicine with three points of poison"
.
Drugs have two sides, and it is inevitable to cause some damage
to the body while achieving a therapeutic effect.
Another important significance of the review is to timely understand the impact of taking drugs on the individual, and adjust the dosage
of drugs in time according to side effects.
Different individuals have different types and dosages of medications, and after regular review, doctors can adjust the plan in time according to the changes in the condition and the response to the drug, and when the disease is controlled, reduce the drug in time to achieve the best treatment effect
.
For example, long-term use of glucocorticoids will not only make people gain weight, slow wound healing, but also cause water and salt metabolism disorders and induce high blood pressure
.
During the review, attention should be paid to checking the relevant indicators
of renal function, blood pressure and other hormonal side effects evaluation.
Long-term use of immunosuppressants, will damage liver and kidney function, cause gastrointestinal discomfort and other side effects, during the review, the doctor will check the liver and kidney gastrointestinal function according to the degree of adverse reactions, timely treatment, if necessary, communicate with the patient whether to change the drug
.
3.
Check according to the previous inspection
When going to the outpatient review, it is very important to remember to bring the previous case information during the review, including the discharge summary, outpatient medical record book, important examination result report form, etc
.
Doctors are able to quickly and targeted tests
based on past medical history and examination reports.
For example, the patient Xiaohong is in the active phase of SLE, the results of the last examination indicate renal impairment, and urinalysis shows urine protein "+++", indicating proteinuria
.
During this review, the doctor can focus on whether there are recent lower back and abdominal pain, hematuria, proteinuria and other related manifestations, and focus on renal function, urinalysis and other renal system-related items
.
How often is it reviewed?
The frequency of re-examination has always been a question that many people wonder, and some patients have asked: "Why can she be rechecked every few months, and I have to go in two weeks?" ”
The answer is: the frequency of follow-up is also determined by
the condition.
The general rule is: two weeks after initial treatment, the first follow-up is performed; Thereafter, the active phase of the disease is reviewed once a month; The stable period of the condition is repeated once every 3-6 months [3];
The purpose of the two-week review is to see how well an individual tolerates the drug and to see if there are side effects and side
effects.
The active phase refers to the current active progression of the disease, the disease changes are more dangerous, and it is easy to have organ involvement, so the progress
of the disease should be observed at least once a month.
At the same time, the active phase may be accompanied by high-dose shock hormone therapy, and the review is also to observe the side effects of
the drug.
When the disease control tends to be stable, and the related symptoms and visceral involvement gradually alleviate, SLE enters a stable period, and then a review every 3-6 months can be done
.
The time for review is not exactly according to this rule, and depending on the situation, the time may be fine-tuned
.
Therefore, remember to make an appointment with the doctor for the next review after the review, so you are not afraid to miss it
.
Many people often have this misconception: "Discharge is rehabilitation, review is a waste of money"
.
This recognition will not only allow the disease to exploit loopholes, but also make us unable to cut off the signs of recurrence in time
.
Therefore, timely review and control the changes in the condition in your own hands is the way
to recover from SLE.
Systemic lupus erythematosus
Can it be cured?